Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.41 |
| ▸ | FEN1 | P39748 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | KAT7 | O95251 | 1/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.38 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2791259 | 0.88 | ALOX5AP (0.43) | TRPV3USP30ALOX5APFEN1SCN9A | |
| SCHEMBL2789214 | 0.86 | CNR2 (0.44) | TRPV3USP30ALOX5APFEN1SCN9A | |
| SCHEMBL2789464 | 0.83 | HPGDS (0.41) | USP30ALOX5APFEN1HPGDS | |
| SCHEMBL7900706 | 0.82 | ALOX5AP (0.42) | TRPV3USP30ALOX5APFEN1SCN9A | |
| SCHEMBL7901024 | 0.81 | ALOX5AP (0.41) | TRPV3USP30ALOX5APFEN1SCN9A | |
| SCHEMBL2789050 | 0.79 | PIK3CD (0.39) | TRPV3ALOX5APFEN1SCN9APDE4B | |
| SCHEMBL2789048 | 0.79 | PIK3CD (0.39) | TRPV3ALOX5APFEN1SCN9APDE4B | |
| SCHEMBL2789961 | 0.79 | ALOX5AP (0.40) | TRPV3USP30ALOX5APFEN1SCN9A | |
| SCHEMBL2791498 | 0.77 | PIK3CD (0.39) | ALOX5APFEN1SCN9APDE4BHPGDS | |
| SCHEMBL2791496 | 0.77 | PIK3CD (0.39) | ALOX5APFEN1SCN9APDE4BHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |