Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL427876 | 0.89 | CNR2 (0.39) | CNR2GRM5KDM4EALDH1A1CYP1A2 | |
| SCHEMBL427139 | 0.80 | CNR2 (0.37) | CNR2GRM5KDM4EALDH1A1CYP1A2 | |
| SCHEMBL427537 | 0.76 | GABRA5 (0.38) | CNR2KDM4EALDH1A1CYP1A2GLA | |
| SCHEMBL425743 | 0.63 | FAAH (0.43) | CNR2GRM5KDM4EALDH1A1CYP1A2 | |
| SCHEMBL427872 | 0.63 | ALDH1A1 (0.36) | CNR2KDM4EALDH1A1CYP1A2GLA | |
| SCHEMBL425991 | 0.63 | ALDH1A1 (0.40) | CNR2KDM4EALDH1A1CYP1A2GLA | |
| SCHEMBL426016 | 0.62 | MAP4K4 (0.42) | CNR2KDM4EALDH1A1CYP1A2GLA | |
| SCHEMBL427656 | 0.61 | DPP4 (0.33) | CNR2KDM4EALDH1A1CYP1A2GLA | |
| SCHEMBL425981 | 0.61 | MIF (0.36) | CNR2KDM4EHSD17B10CNR1 | |
| SCHEMBL425883 | 0.61 | KDM1A (0.33) | CNR2GRM5KDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074588-A2 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2010-07-01 | — | — | WO | disclosed |