Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITPR3 | Q14573 | 2/20 | 0.32 |
| ▸ | ITPR2 | Q14571 | 1/20 | 0.32 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4391083 | 0.78 | LGALS1 (0.45) | FBP1 | |
| SCHEMBL19946 | 0.75 | LGALS1 (0.42) | FBP1 | |
| Phosphoric Acid SCHEMBL8812339 | 0.68 | CA9 (0.38) | ITPR3ITPR2ITPR1FBP1 | |
| SCHEMBL4903004 | 0.68 | CA2 (0.31) | — | |
| SCHEMBL14191363 | 0.67 | GBA1 (0.47) | — | |
| SCHEMBL10076292 | 0.67 | GBA1 (0.47) | — | |
| SCHEMBL9613597 | 0.67 | GBA1 (0.47) | — | |
| SCHEMBL16812686 | 0.67 | GBA1 (0.47) | — | |
| SCHEMBL22043674 | 0.67 | GBA1 (0.47) | — | |
| SCHEMBL14191362 | 0.67 | GBA1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0642799-B1 | Improved prodrugs for enzyme mediated activation | HOECHST AG (DE) | 2001-11-07 | — | — | EP | disclosed |
| US-5621002-A | HAVING A MODIFIED COMPETITIVE ENZYME ACTIVITY INHBITOR LINKED TO A SPACER-DRUG; ENZYME CLEAVAGE AT A LOWER CONCENTRATION, I.E. LOW MICHAELIS-MENTEN CONSTANT(KM) | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1997-04-15 | — | — | US | disclosed |
| EP-0642799-A1 | Improved prodrugs for enzyme mediated activation | BEHRINGWERKE Aktiengesellschaft (DE) | 1995-03-15 | — | — | EP | disclosed |