SCHEMBL4903004

SCHEMBL4903004

O=P(O)(O)C1OC1P(=O)(O)O

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.31
LMNA P02545 2/20 0.30
MAPT P10636 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30
CYP2C9 P11712 1/20 0.30
TSHR P16473 1/20 0.30
ALOX12 P18054 1/20 0.30
NFKB1 P19838 1/20 0.30
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fosfomycin SCHEMBL5595663 0.76 LMNA (0.50) CA2LMNAMAPTBLMPMP22
Fosfomycin SCHEMBL50951 0.76
Fosfomycin SCHEMBL9634477 0.76
Fosfomycin SCHEMBL989825 0.76
Fosfomycin SCHEMBL3168937 0.76
Fosfomycin SCHEMBL3168929 0.76
Fosfomycin SCHEMBL8633252 0.76
Fosfomycin SCHEMBL10492648 0.76
Fosfomycin SCHEMBL989824 0.74
Fosfomycin SCHEMBL9634052 0.74 LMNA (0.48) CA2LMNAMAPTBLMPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0590009-B1 DIALKYL (DIALKOXYPHOSPHINYL)METHYL PHOSPHATES AS ANTI-INFLAMMATORY AGENTS UPJOHN CO (US) 1998-03-18 EP claimed
US-20080226565-A1 Anticariogenic Proteins & Peptides & Saccharides HUYBRECHTS LUCAS 2008-09-18 US disclosed
EP-1709069-A2 ANTICARIOGENIC PROTEINS AND PEPTIDES & SACCHARIDES Huybrechts, Lucas (BE) 2006-10-11 EP disclosed
WO-2005068645-A2 ANTICARIOGENIC PROTEINS & PEPTIDES & SACCHARIDES HUYBRECHTS LUCAS (BE) 2005-07-28 WO disclosed