4-Nitroaniline

4-Nitroaniline

SCHEMBL790126

COc1ccc(OC)c(N)c1.Nc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 1/20 0.69
▸ ALDH1A1 P00352 8/20 0.60
▸ KMT2A Q03164 6/20 0.60
▸ MAPT P10636 6/20 0.60
▸ MEN1 O00255 4/20 0.60
▸ THRB P10828 1/20 0.60
▸ HTT P42858 2/20 0.58
▸ TLR9 Q9NR96 1/20 0.56
▸ PDE7A Q13946 1/20 0.52
▸ PTGS2 P35354 2/20 0.48
▸ PKM P14618 1/20 0.48
▸ CYP19A1 P11511 1/20 0.48
▸ CYP3A4 P08684 1/20 0.47
▸ LMNA P02545 2/20 0.47
▸ CRHBP P24387 1/20 0.47
▸ CRHR2 Q13324 1/20 0.47
▸ POLB P06746 1/20 0.47
▸ APP P05067 1/20 0.46
▸ PTGS1 P23219 1/20 0.46
▸ RECQL P46063 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8020422 0.84 ALDH1A1 (0.69) TDP1ALDH1A1KMT2AMAPTMEN1
SCHEMBL269845 0.82 TDP1 (1.00) TDP1ALDH1A1KMT2AMAPTMEN1
SCHEMBL3462835 0.82 TDP1 (1.00) TDP1ALDH1A1KMT2AMAPTMEN1
Ammonia Solution, Strong SCHEMBL10880861 0.81 TDP1 (0.96) TDP1ALDH1A1KMT2AMAPTMEN1
Hydrochloric Acid SCHEMBL21772081 0.81 TDP1 (0.96) TDP1ALDH1A1KMT2AMAPTMEN1
Aniline SCHEMBL22169236 0.81 TDP1 (0.82) TDP1ALDH1A1KMT2AMAPTMEN1
SCHEMBL4229181 0.79 ALDH1A1 (0.69) TDP1ALDH1A1KMT2AMAPTMEN1
SCHEMBL4687037 0.79 ALDH1A1 (0.61) TDP1ALDH1A1KMT2AMAPTMEN1
SCHEMBL4237867 0.79 ALDH1A1 (0.61) TDP1ALDH1A1KMT2AMAPTMEN1
SCHEMBL92071 0.79 ALDH1A1 (0.95) TDP1ALDH1A1KMT2AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10996218-B2 Methods for chemotaxis / redox driven separation of X and Y chromosome bearing sperm and their insemination in gender specific menstrual cycles OURNEXTBABY LLC (US) 2021-05-04 — — US disclosed
US-20180292399-A1 METHODS FOR CHEMOTAXIS / REDOX DRIVEN SEPARATION OF X AND Y CHROMOSOME BEARING SPERM AND THEIR INSEMINATION IN GENDER SPECIFIC MENSTRUAL CYCLES GENDERQUEST LLC (US) 2018-10-11 — — US disclosed
US-10018625-B2 Use of female mammal's urine for determination of fetal gender related characteristics UROBIOLOGICS LLC (US) 2018-07-10 — — US disclosed
EP-2863220-B1 Reducing/oxidizing activity of maternal urine as indicator of fetal gender related characteristics UROBIOLOGICS LLC (US) 2017-09-06 — — EP disclosed
EP-2619573-B1 USE OF FEMALE MAMMAL'S URINE FOR DETERMINATION OF FETAL GENDER RELATED CHARACTERISTICS UROBIOLOGICS LLC (US) 2017-06-14 — — EP disclosed
US-20150316540-A1 REDUCING/OXIDIZING ACTIVITY OF MATERNAL URINE AS INDICATOR OF FETAL GENDER RELATED CHARACTERISTICS UROBIOLOGICS LLC 2015-11-05 — — US disclosed
US-9057720-B2 Reducing/oxidizing activity of maternal urine as indicator of fetal gender related characteristics UROBIOLOGICS LLC (US) 2015-06-16 — — US disclosed
EP-2863220-A2 Reducing/oxidizing activity of maternal urine as indicator of fetal gender related characteristics Urobiologics LLC (US) 2015-04-22 — — EP disclosed
US-20140302537-A1 Use of Female Mammal's Urine for Determination of Fetal Gender Related Characteristics OURNEXTBABY LLC 2014-10-09 — — US disclosed
US-8759109-B2 Use of female mammal's urine for determination of fetal gender related characteristics UROBIOLOGICS LLC (US) 2014-06-24 — — US disclosed
EP-2619573-A1 USE OF FEMALE MAMMAL'S URINE FOR DETERMINATION OF FETAL GENDER RELATED CHARACTERISTICS Urobiologics LLC (US) 2013-07-31 — — EP disclosed
WO-2012036691-A1 USE OF FEMALE MAMMAL'S URINE FOR DETERMINATION OF FETAL GENDER RELATED CHARACTERISTICS UROBIOLOGICS LLC (US) 2012-03-22 — — WO disclosed
US-20110230453-A1 Use of Female Mammal's Urine for Determination of Fetal Gender Related Characteristics UROBIOLOGICS LLC (US) 2011-09-22 — — US disclosed
EP-2257803-A2 REDUCING/OXIDIZING ACTIVITY OF MATERNAL URINE AS INDICATOR OF FETAL GENDER RELATED CHARACTERISTICS Urobiologics LLC (US) 2010-12-08 — — EP disclosed
WO-2009114579-A2 REDUCING/OXIDIZING ACTIVITY OF MATERNAL URINE AS INDICATOR OF FETAL GENDER RELATED CHARACTERISTICS UROBIOGICS LLC (US) 2009-09-17 — — WO disclosed
US-20090233321-A1 Reducing/Oxidizing Activity of Maternal Urine As Indicator of Fetal Gender Related Characteristics UROBIOLOGICS LLC (US) 2009-09-17 — — US disclosed
US-4160696-A Ascorbic acid determination EASTMAN KODAK COMPANY (US) 1979-07-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110230453-A1 Use of Female Mammal's Urine for Determination of Fetal Gender Related Characteristics SHBG, PGF, CYP19A1 TDP1 3082/4885ALDH1A1 243/4885KMT2A 4397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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