SCHEMBL7901426

SCHEMBL7901426

O=c1cc(C(F)(F)F)n2ccnc2n1-c1cc(NS(=O)(=O)CCl)c(Cl)cc1F

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8122021 0.93 MCL1 (0.34) MCL1
SCHEMBL7901513 0.89 PPOX (0.36) MCL1
SCHEMBL8137586 0.82 MCL1 (0.33) MCL1
SCHEMBL7903043 0.79 GAA (0.32)
SCHEMBL8137614 0.79
SCHEMBL8136011 0.79
SCHEMBL8137605 0.77
SCHEMBL7901378 0.77 L3MBTL1 (0.41)
SCHEMBL7894127 0.76 MAPK1 (0.31)
SCHEMBL7901544 0.76 PPOX (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6191070-B1 Pyrimidinone derivatives and herbicides containing them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-02-20 US claimed
EP-0902029-A1 Pyrimidinone derivatives and herbicides containing them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-17 EP disclosed