SCHEMBL7901436

SCHEMBL7901436

CC(C)(C)Nc1ccc(C(=O)c2ccc(NC(C)(C)C)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
HPGD P15428 5/20 0.47
RAB9A P51151 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
MAPK13 O15264 1/20 0.47
MAPK12 P53778 1/20 0.47
MAPK11 Q15759 1/20 0.47
MAPK14 Q16539 1/20 0.47
LMNA P02545 3/20 0.46
SRD5A2 P31213 2/20 0.45
ABCC9 O60706 3/20 0.45
ABCC8 Q09428 3/20 0.45
KCNJ11 Q14654 3/20 0.45
KCNJ8 Q15842 3/20 0.45
PDK1 Q15118 2/20 0.45
PDK2 Q15119 2/20 0.45
PDK3 Q15120 2/20 0.45
PDK4 Q16654 2/20 0.45
ABCB11 O95342 1/20 0.45
ELANE P08246 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12883549 0.84 MAPT (0.50) ALDH1A1HPGDRAB9AL3MBTL1LMNA
SCHEMBL195265 0.84 ALDH1A1 (0.50) ALDH1A1HPGDRAB9AL3MBTL1MAPK13
SCHEMBL1711131 0.84 EPHX2 (0.55) ALDH1A1HPGDRAB9ASRD5A2MEN1
SCHEMBL10079948 0.83 L3MBTL1 (0.43) ALDH1A1HPGDRAB9AL3MBTL1LMNA
SCHEMBL12403813 0.83 ALDH1A1 (0.50) ALDH1A1RAB9AL3MBTL1MEN1NPC1
SCHEMBL13348869 0.81 MAPT (0.50) ALDH1A1HPGDRAB9AL3MBTL1LMNA
SCHEMBL10283605 0.81 LMNA (0.53) LMNAKMT2ASMN1; SMN2HTTMAPT
SCHEMBL10294115 0.81 HDAC8 (0.55) HPGDRAB9ANPC1SMN1; SMN2HTT
SCHEMBL12403814 0.81 MEN1 (0.56) ALDH1A1HPGDRAB9ALMNAMEN1
SCHEMBL4603900 0.80 IDO1 (0.39) ALDH1A1HPGDRAB9AL3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6200718-B1 A POLYMERIZED TONER OF CORE-SHELL STRUCTURE, COMPRISING CORE PARTICLES COMPOSED OF COLORED POLYMER PARTICLES WHICH CONTAIN A COMPOUND HAVING >C=N+ STRUCTURE IN ITS MOLECULE AND A COLORANT AND A LAYER OF POLYMER COVERING CORE PARTICLES NIPPON ZEON CO., LTD. (JP) 2001-03-13 US disclosed
EP-0947888-A1 POLYMER TONER AND METHOD OF PRODUCTION THEREOF NIPPON ZEON CO., LTD. (JP) 1999-10-06 EP disclosed
EP-0438248-B1 Preparation process of toner NIPPON ZEON CO (JP) 1996-07-24 EP disclosed
US-5217839-A Dispersion containing mixture of a polymer with a carbon nitrogen double bond and a colorant in a vinyl monomer NIPPON ZEON CO., LTD. (JP) 1993-06-08 US disclosed
EP-0438248-A2 Preparation process of toner NIPPON ZEON CO., LTD. (JP) 1991-07-24 EP disclosed