Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 16/20 | 0.61 |
| ▸ | MMP2 | P08253 | 17/20 | 0.61 |
| ▸ | MMP3 | P08254 | 14/20 | 0.61 |
| ▸ | MMP1 | P03956 | 5/20 | 0.60 |
| ▸ | MMP9 | P14780 | 3/20 | 0.60 |
| ▸ | MMP8 | P22894 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7587409 | 0.92 | MMP13 (0.61) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7454637 | 0.89 | MMP13 (0.78) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7572575 | 0.86 | MMP13 (0.65) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7445843 | 0.85 | MMP13 (0.82) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7446824 | 0.85 | MMP13 (0.70) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7903561 | 0.85 | MMP13 (0.67) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7502956 | 0.85 | MMP13 (0.81) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7456191 | 0.85 | MMP2 (0.81) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7450637 | 0.84 | MMP2 (0.86) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7899846 | 0.83 | MMP2 (0.68) | MMP13MMP2MMP3MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | disclosed |