Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 17/20 | 0.81 |
| ▸ | MMP13 | P45452 | 15/20 | 0.81 |
| ▸ | MMP3 | P08254 | 13/20 | 0.81 |
| ▸ | MMP9 | P14780 | 5/20 | 0.62 |
| ▸ | MMP1 | P03956 | 4/20 | 0.62 |
| ▸ | MMP8 | P22894 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450637 | 0.90 | MMP2 (0.86) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL4371861 | 0.89 | MMP2 (0.64) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL7572575 | 0.88 | MMP13 (0.65) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL7502956 | 0.87 | MMP13 (0.81) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL7587409 | 0.85 | MMP13 (0.61) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL7502697 | 0.85 | MMP13 (0.80) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL7901576 | 0.85 | MMP13 (0.61) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL7502269 | 0.85 | MMP13 (0.86) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL2904532 | 0.80 | MMP2 (0.81) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL7506676 | 0.79 | MMP2 (0.86) | MMP2MMP13MMP3MMP9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165501-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000051975-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |