⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL693830 | 0.71 | — | — | |
| SCHEMBL8363499 | 0.70 | — | — | |
| SCHEMBL2744267 | 0.69 | CA1 (0.33) | — | |
| SCHEMBL2319750 | 0.67 | — | — | |
| SCHEMBL215513 | 0.67 | CA1 (0.32) | — | |
| SCHEMBL28255346 | 0.66 | CA2 (0.37) | — | |
| SCHEMBL6325095 | 0.62 | — | — | |
| SCHEMBL27725055 | 0.62 | — | — | |
| SCHEMBL14712451 | 0.62 | F2 (0.30) | — | |
| SCHEMBL7547616 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427694-B1 | Synthesis of mannojirimycin derivatives | MONSANTO CO (US) | 1994-05-04 | — | — | EP | claimed |
| EP-0427694-A1 | Synthesis of mannojirimycin derivatives | MONSANTO COMPANY (US) | 1991-05-15 | — | — | EP | claimed |
| US-5011929-A | From protected azidolactone by reduction and cyclization | MONSANTO COMPANY (US) | 1991-04-30 | — | — | US | claimed |
| JP-3127775-A | — | — | None | — | — | JP | disclosed |
| CN-114437157-A | Sialic acid Neu5Ac derivative and preparation method and application thereof | 深圳先进技术研究院 | 2022-05-06 | — | — | CN | disclosed |
| US-10351591-B2 | Polypeptides, peptides, and proteins functionalized by alkylation of thioether groups via ring-opening reactions | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-07-16 | — | — | US | disclosed |
| US-20180105553-A1 | POLYPEPTIDES, PEPTIDES, AND PROTEINS FUNCTIONALIZED BY ALKYLATION OF THIOETHER GROUPS VIA RING-OPENING REACTIONS | NATIONAL SCIENCE FOUNDATION | 2018-04-19 | — | — | US | disclosed |
| WO-2016154120-A1 | POLYPEPTIDES, PEPTIDES, AND PROTEINS FUNCTIONALIZED BY ALKYLATION OF THIOETHER GROUPS VIA RING-OPENING REACTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-09-29 | — | — | WO | disclosed |
| EP-2710027-A1 | BOMBESIN RECEPTOR TARGETING PEPTIDE INCORPORATING A 1, 2, 3-TRIAZOLE GROUP IN THE BACKBONE FOR PREPARING IN VIVO DIAGNOSTIC AND THERAPEUTIC AGENTS | Universitätsspital Basel (CH) | 2014-03-26 | — | — | EP | disclosed |
| WO-2012156511-A1 | BOMBESIN RECEPTOR TARGETING PEPTIDE INCORPORATING A 1, 2, 3-TRIAZOLE GROUP IN THE BACKBONE FOR PREPARING IN VIVO DIAGNOSTIC AND THERAPEUTIC AGENTS | UNIVERSITÄTSSPITAL BASEL (CH) | 2012-11-22 | — | — | WO | disclosed |
| US-6197963-B1 | TETRAHYDROPYRAN DERIVATIVES; PROTEIN G, SOMATOSTATIN, AND NATURAL KILLER CELL RECEPTOR ANTAGONISTS OR MIMETICS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2001-03-06 | — | — | US | disclosed |
| US-5075448-A | Synthesis of swainsonine and analogs thereof | MONSANTO COMPANY (US) | 1991-12-24 | — | — | US | disclosed |
| US-5023340-A | Pyrrolizioines and synthesis thereof | MONSANTO COMPANY (US) | 1991-06-11 | — | — | US | disclosed |
| US-5021562-A | Chemical intermediates | MONSANTO COMPANY (US) | 1991-06-04 | — | — | US | disclosed |
| JP-H03127775-A | SYNTHESIS OF MANNOJIRIMYCIN DERIVATIVE | MONSANTO CO | 1991-05-30 | — | — | JP | disclosed |
| EP-0427693-A1 | Method for azide displacement of alpha-triflates of 1,5-lactones | MONSANTO COMPANY (US) | 1991-05-15 | — | — | EP | disclosed |
| EP-0427694-A1 | Synthesis of mannojirimycin derivatives | MONSANTO COMPANY (US) | 1991-05-15 | — | — | EP | disclosed |
| US-5011929-A | From protected azidolactone by reduction and cyclization | MONSANTO COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| EP-0424349-A1 | Synthesis of 1,4-dideoxy-1,4-imino-D-mannitol | MONSANTO COMPANY (US) | 1991-04-24 | — | — | EP | disclosed |
| EP-0423099-A1 | Synthesis of nojirimycin derivatives | Monsanto Company (US) | 1991-04-17 | — | — | EP | disclosed |