⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4673500 | 0.84 | — | — | |
| SCHEMBL12088001 | 0.83 | THRB (0.46) | — | |
| SCHEMBL9569864 | 0.83 | TRPA1 (0.33) | — | |
| SCHEMBL28140750 | 0.80 | THRB (0.44) | — | |
| SCHEMBL29635180 | 0.80 | — | — | |
| SCHEMBL270904 | 0.80 | — | — | |
| SCHEMBL4567264 | 0.78 | TSHR (0.52) | — | |
| SCHEMBL230055 | 0.78 | — | — | |
| SCHEMBL106813 | 0.76 | — | — | |
| SCHEMBL18214425 | 0.76 | THRB (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122080417-A | Cast-in-place concrete hydration heat optimal control method for lock mass concrete structure | — | 2026-05-26 | — | — | CN | disclosed |
| CN-109071526-B | Acid addition salts of piperazine derivatives | 阿森纽荣股份公司 | 2023-02-28 | — | — | CN | disclosed |
| WO-2022087371-A1 | NOVEL BICYCLIC COMPOUNDS | SPECTRUM PHARMACEUTICALS, INC. (US) | 2022-04-28 | — | — | WO | disclosed |
| CN-111138402-B | Preparation method of isocoumarin derivative | 苏州大学 | 2021-11-23 | — | — | CN | disclosed |
| CN-108218809-B | Synthetic method of medicine intermediate 2-aminothiazole-4-ethyl formate | 宁夏法安德药业有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-111138402-A | Preparation method of isocoumarin derivative | 苏州大学 | 2020-05-12 | — | — | CN | disclosed |
| US-10435756-B2 | Selective inhibitors of tumor-initiating cells | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2019-10-08 | — | — | US | disclosed |
| US-10093663-B2 | Piperidinyl-indole derivatives complement factor B inhibitors and uses thereof | NOVARTIS AG (CH) | 2018-10-09 | — | — | US | disclosed |
| US-20180105883-A1 | SELECTIVE INHIBITORS OF TUMOR-INITIATING CELLS | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2018-04-19 | — | — | US | disclosed |
| EP-3299365-A1 | PIPERIDINYL-INDOLE DERIVATIVES COMPLEMENT FACTOR B INHIBITORS AND USES THEREOF | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |
| US-20020193405-A1 | Thiazolyl urea compounds and methods of uses | AMGEN INC. | 2002-12-19 | — | — | US | disclosed |
| WO-2002092576-A1 | DIARYLUREA DERIVATIVES USEFUL AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-11-21 | — | — | WO | disclosed |
| US-20020173507-A1 | Urea compounds and methods of uses | AMGEN INC. | 2002-11-21 | — | — | US | disclosed |
| EP-1250334-A2 | AGENTS AND METHODS FOR THE TREATMENT OF PROLIFERATIVE DISEASES | ELI LILLY AND COMPANY (US) | 2002-10-23 | — | — | EP | disclosed |
| EP-1242420-A2 | AGENTS AND METHODS FOR THE TREATMENT OF PROLIFERATIVE DISEASES | ELI LILLY AND COMPANY (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2002014311-A2 | UREA COMPOUNDS AND METHODS OF USES | AMGEN INC. (US) | 2002-02-21 | — | — | WO | disclosed |
| WO-2001044235-A2 | AGENTS AND METHODS FOR THE TREATMENT OF PROLIFERATIVE DISEASES | ELI LILLY AND COMPANY (US) | 2001-06-21 | — | — | WO | disclosed |
| WO-2001044247-A2 | AGENTS AND METHODS FOR THE TREATMENT OF PROLIFERATIVE DISEASES | ELI LILLY AND COMPANY (US) | 2001-06-21 | — | — | WO | disclosed |
| CN-1045441-C | Antifungal agent, and preparation method and intermediate thereof | EISAI CO LTD (JP) | 1999-10-06 | — | — | CN | disclosed |
| CN-1113241-A | Antifungal agent, and preparation method and intermediate thereof | EISAI CO LTD (JP) | 1995-12-13 | — | — | CN | disclosed |