Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7895782 | 0.88 | ITGB3 (0.48) | ITGB3ITGA2BLMNAKDM4ETSHR | |
| SCHEMBL17244439 | 0.83 | ITGB3 (0.51) | ITGB3ITGA2BLMNAKDM4EALOX15 | |
| SCHEMBL7895593 | 0.82 | ITGB3 (0.38) | ITGB3ITGA2BKDM4ETSHRALDH1A1 | |
| SCHEMBL12545824 | 0.80 | ITGB3 (0.48) | ITGB3ITGA2BKDM4EALOX15TSHR | |
| SCHEMBL38662990 | 0.77 | KDM4E (0.54) | ITGB3ITGA2BKDM4EALOX15TSHR | |
| SCHEMBL17244437 | 0.70 | ITGB3 (0.45) | ITGB3ITGA2BKDM4ETSHRALDH1A1 | |
| SCHEMBL12870511 | 0.68 | PRMT5 (0.38) | ITGB3ITGA2BALOX15CYP3A4KMT2A | |
| SCHEMBL12545649 | 0.68 | ITGB3 (0.43) | ITGB3ITGA2BLMNATSHRCYP3A4 | |
| SCHEMBL21481250 | 0.67 | HTR2A (0.46) | ITGB3ITGA2BLMNAKDM4EALOX15 | |
| SCHEMBL7931439 | 0.67 | KDM4E (0.45) | KDM4EALOX15TSHRSIRT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373634-B1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARM CO LTD (JP) | 2015-11-11 | — | — | EP | disclosed |
| WO-2010065717-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |