Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | HPGD | P15428 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 8/20 | 0.41 |
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | STAT1 | P42224 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991921 | 0.81 | RAB9A (0.53) | MAPTALDH1A1HPGDKDM4ETDP1 | |
| SCHEMBL20855087 | 0.77 | ALDH1A1 (0.54) | MAPTALDH1A1KDM4ETDP1NPC1 | |
| 2-Phenylbenzo[D]Oxazole SCHEMBL3859759 | 0.73 | NPC1 (0.48) | MAPTALDH1A1HPGDKDM4EUSP2 | |
| SCHEMBL900790 | 0.72 | ALDH1A1 (0.56) | MAPTALDH1A1HPGDKDM4ETDP1 | |
| SCHEMBL824375 | 0.71 | NPC1 (0.69) | MAPTALDH1A1HPGDKDM4EUSP2 | |
| SCHEMBL29531707 | 0.71 | NPC1 (0.69) | MAPTALDH1A1HPGDKDM4EUSP2 | |
| SCHEMBL4159029 | 0.71 | NPC1 (0.67) | MAPTALDH1A1HPGDKDM4EUSP2 | |
| SCHEMBL28774905 | 0.70 | KDM4E (0.55) | MAPTALDH1A1HPGDKDM4EUSP2 | |
| SCHEMBL10779720 | 0.69 | ALDH1A1 (0.61) | MAPTALDH1A1KDM4ETDP1NPC1 | |
| SCHEMBL21776842 | 0.69 | NPC1 (0.53) | MAPTALDH1A1HPGDKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207464-B1 | INCUBATING TARGET WITH DYE TO FORM A COVALENT BOND; BLUE FLUORESCING DYES | CARNEGIE MELLON UNIVERSITY | 2001-03-27 | — | — | US | disclosed |
| US-5852191-A | Rigidized monomethine cyanines | CARNEGIE MELLON UNIVERSITY (US) | 1998-12-22 | — | — | US | disclosed |