Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 11/20 | 0.68 |
| ▸ | EGFR | P00533 | 1/20 | 0.63 |
| ▸ | PPARG | P37231 | 1/20 | 0.62 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | SNCA | P37840 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902110 | 1.00 | NFE2L2 (0.68) | NFE2L2EGFRPPARGTRPA1ALDH1A1 | |
| SCHEMBL7904281 | 0.93 | NFE2L2 (0.72) | NFE2L2EGFRPPARGTRPA1ALDH1A1 | |
| SCHEMBL7904278 | 0.93 | NFE2L2 (0.72) | NFE2L2EGFRPPARGTRPA1ALDH1A1 | |
| SCHEMBL28341391 | 0.91 | NFE2L2 (0.79) | NFE2L2EGFRPPARGALDH1A1LMNA | |
| SCHEMBL28341395 | 0.85 | NFE2L2 (0.70) | NFE2L2PPARGALDH1A1RELA | |
| SCHEMBL28341396 | 0.85 | NFE2L2 (0.70) | NFE2L2PPARGALDH1A1RELA | |
| SCHEMBL1194740 | 0.84 | NFE2L2 (0.68) | NFE2L2ALDH1A1LMNAMAPTCYP3A4 | |
| SCHEMBL1194737 | 0.84 | NFE2L2 (0.68) | NFE2L2ALDH1A1LMNAMAPTCYP3A4 | |
| SCHEMBL7896106 | 0.83 | RELA (0.63) | NFE2L2EGFRMAPTRELA | |
| SCHEMBL7896104 | 0.83 | RELA (0.63) | NFE2L2EGFRMAPTRELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332900-B | Olefin compound and synthesis method thereof | 华中科技大学 | 2024-12-06 | — | — | CN | claimed |
| CN-116332900-A | Olefin compound and synthesis method thereof | 华中科技大学 | 2023-06-27 | — | — | CN | claimed |
| CN-116332900-B | Olefin compound and synthesis method thereof | 华中科技大学 | 2024-12-06 | — | — | CN | disclosed |
| CN-117430125-A | Preparation method and application of manganese doped mesoporous structure-containing acidic Beta zeolite molecular sieve | 常州大学 | 2024-01-23 | — | — | CN | disclosed |
| CN-116332900-A | Olefin compound and synthesis method thereof | 华中科技大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-108623503-B | Green preparation method of vinyl sulfone derivative in water phase | 宁波大学 | 2020-01-03 | — | — | CN | disclosed |
| US-6201131-B1 | REACTING A 2-(ARYLSUFONYL) ETHANOL DERIVATIVE WITH AN ACID ANHYDRIDE IN PRESENCE OF A BASE, FURTHER REACTING THIS WITH AN AROMATIC HALIDE IN THE PRESENCE OF A PALLADIUM CATALYST; USEFUL AS INTERMEDIATES TO DRUGS, AGROCHEMICALS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-03-13 | — | — | US | disclosed |