Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 12/20 | 0.72 |
| ▸ | PPARG | P37231 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904278 | 1.00 | NFE2L2 (0.72) | NFE2L2PPARGALDH1A1LMNATRPA1 | |
| SCHEMBL7902113 | 0.93 | NFE2L2 (0.68) | NFE2L2PPARGALDH1A1LMNATRPA1 | |
| SCHEMBL7902110 | 0.93 | NFE2L2 (0.68) | NFE2L2PPARGALDH1A1LMNATRPA1 | |
| SCHEMBL28341391 | 0.91 | NFE2L2 (0.79) | NFE2L2PPARGALDH1A1LMNAEGFR | |
| SCHEMBL28341395 | 0.85 | NFE2L2 (0.70) | NFE2L2PPARGALDH1A1MEN1MAOB | |
| SCHEMBL28341396 | 0.85 | NFE2L2 (0.70) | NFE2L2PPARGALDH1A1MEN1MAOB | |
| SCHEMBL1194737 | 0.84 | NFE2L2 (0.68) | NFE2L2ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL1194740 | 0.84 | NFE2L2 (0.68) | NFE2L2ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL28796892 | 0.83 | TRPA1 (0.53) | NFE2L2PPARGALDH1A1LMNATRPA1 | |
| SCHEMBL5572469 | 0.82 | TLR9 (0.64) | NFE2L2PPARGALDH1A1LMNAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096158-B | Preparation method of (E) -alkenyl sulfone compound | 石家庄学院 | 2020-06-12 | — | — | CN | disclosed |
| US-6201131-B1 | REACTING A 2-(ARYLSUFONYL) ETHANOL DERIVATIVE WITH AN ACID ANHYDRIDE IN PRESENCE OF A BASE, FURTHER REACTING THIS WITH AN AROMATIC HALIDE IN THE PRESENCE OF A PALLADIUM CATALYST; USEFUL AS INTERMEDIATES TO DRUGS, AGROCHEMICALS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-03-13 | — | — | US | disclosed |