Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.42 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31413031 | 1.00 | GPR35 (0.47) | GPR35ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL1494608 | 0.85 | CYP3A4 (0.52) | GPR35ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL6121980 | 0.84 | ALDH1A1 (0.47) | GPR35ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL2961900 | 0.84 | ALDH1A1 (0.51) | GPR35ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL18830361 | 0.84 | GPR35 (0.46) | GPR35ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL31402002 | 0.84 | TTR (0.41) | GPR35ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL10584469 | 0.82 | GPR35 (0.44) | GPR35ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL27183608 | 0.82 | DHODH (0.49) | GPR35ALDH1A1TSHRHPGDTDP1 | |
| SCHEMBL10558853 | 0.80 | TSHR (0.47) | GPR35ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL12000739 | 0.80 | TDP1 (0.49) | GPR35ALDH1A1VCAM1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119306607-A | 3-Amino-2-fluorobenzamide compound and preparation method thereof | 江西天宇化工有限公司 | 2025-01-14 | — | — | CN | claimed |
| CN-119306607-A | 3-Amino-2-fluorobenzamide compound and preparation method thereof | 江西天宇化工有限公司 | 2025-01-14 | — | — | CN | disclosed |
| US-6201119-B1 | 2,3,4,5-TETRAHYDRO-1H-1,4-BENZODIAZEPIN-9-AMINE COMPOUNDS USEFUL AS INTERMEDIATES TO ANTIVIRALS | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-03-13 | — | — | US | disclosed |
| US-5371079-A | Administering to inhibit replication of HIV-1 in human cells | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-12-06 | — | — | US | disclosed |
| US-5270464-A | Anti-HIV-1 tetrahydroimidazo[1,4]benzodiazepin-2-(thi) ones | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-12-14 | — | — | US | disclosed |
| US-4067726-A | 3-Ureido phenylacetamide herbicides | BAYER AKTIENGESELLSCHAFT (DT) | 1978-01-10 | — | — | US | disclosed |
| US-4052444-A | DIAZO COUPLERS FOR MONOAZO DYES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-10-04 | — | — | US | disclosed |