Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1487913 | 0.86 | CA1 (0.53) | ALDH1A1GPR35LMNAKMT2AHPGD | |
| SCHEMBL10483657 | 0.84 | ALDH1A1 (0.50) | ALDH1A1GPR35LMNAKMT2AHPGD | |
| Hydrochloric Acid SCHEMBL2961904 | 0.84 | CA1 (0.51) | ALDH1A1GPR35LMNAKMT2AHPGD | |
| SCHEMBL10563402 | 0.84 | ALDH1A1 (0.50) | ALDH1A1GPR35LMNAKMT2AHPGD | |
| SCHEMBL2889129 | 0.84 | ALDH1A1 (0.68) | ALDH1A1GPR35LMNAKMT2AHPGD | |
| SCHEMBL27262068 | 0.84 | ALDH1A1 (0.64) | ALDH1A1GPR35LMNAKMT2AMEN1 | |
| SCHEMBL7902277 | 0.84 | GPR35 (0.47) | ALDH1A1GPR35HPGDMAPK1TTR | |
| SCHEMBL31413031 | 0.84 | GPR35 (0.47) | ALDH1A1GPR35HPGDMAPK1TTR | |
| SCHEMBL3324248 | 0.82 | ALDH1A1 (0.51) | ALDH1A1GPR35LMNAKMT2AHPGD | |
| SCHEMBL6325040 | 0.82 | GPR35 (0.61) | ALDH1A1GPR35LMNAKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102718678-B | Pre-column derivation reagent and preparation process | WUHAN WU PHARMACEUTICAL TECHNOLOGY CO LTD | 2014-12-10 | — | — | CN | claimed |
| CN-102731339-B | Pre-column derivatization agent and its synthesis method | WUHAN WUYAO TECHNOLOGY CO LTD | 2014-07-16 | — | — | CN | claimed |
| CN-102718678-B | Pre-column derivation reagent and preparation process | WUHAN WU PHARMACEUTICAL TECHNOLOGY CO LTD | 2014-12-10 | — | — | CN | disclosed |
| CN-102276598-B | Benzothiazine-thione derivatives, preparation method thereof and purpose thereof | UNIV SICHUAN | 2014-11-05 | — | — | CN | disclosed |
| US-20140303152-A1 | BENZOTHIAZINETHIONE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF | SICHUAN UNIVERSITY (CN) | 2014-10-09 | — | — | US | disclosed |
| CN-102731339-B | Pre-column derivatization agent and its synthesis method | WUHAN WUYAO TECHNOLOGY CO LTD | 2014-07-16 | — | — | CN | disclosed |
| EP-2719691-A1 | BENZOTHIAZINETHIONE DERIVATIVES AND THEIR PREPARATIVE METHODS AND USES | Si Chuan University (CN) | 2014-04-16 | — | — | EP | disclosed |
| CN-102659616-B | Pre-column derivatization reagent and preparation process | HUBEI YUANDA FUCHI PHARMACEUTICAL CHEMICALS CO LTD | 2014-03-26 | — | — | CN | disclosed |
| CN-102276598-A | Benzothiazine-thione derivatives, preparation method thereof and purpose thereof | — | 2011-12-14 | — | — | CN | disclosed |
| US-7776924-B2 | Nitroaniline-based alkylating agents and their use as prodrugs | AUCKLAND UNISERVICES LIMITED (NZ) | 2010-08-17 | — | — | US | disclosed |
| CN-101735083-A | Method for synthesizing dye intermediate of 2-amino-3,5-dinitroacetophenone | UNIV YANGZHOU | 2010-06-16 | — | — | CN | disclosed |
| EP-0004279-B1 | PROCESS FOR THE PREPARATION OF 4-PYRIDONE-3-CARBOXYLIC ACIDS, 1-CYCLOPROPYL-4-PYRIDONE-3-CARBOXYLIC ACID DERIVATIVES AND MEDICINES CONTAINING THEM | BAYER AG (DE) | 1982-12-29 | — | — | EP | disclosed |
| US-4284629-A | ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | disclosed |
| US-4281151-A | ANTIALLERGENS, ANTIANAPHYLACTIC AGENTS | THE UPJOHN COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| US-4186127-A | ANTIALLERGENS | THE UPJOHN COMPANY (US) | 1980-01-29 | — | — | US | disclosed |
| EP-0004279-A1 | Process for the preparation of 4-pyridone-3-carboxylic acids, 1-cyclopropyl-4-pyridone-3-carboxylic acid derivatives and medicines containing them | BAYER AG (DE) | 1979-10-03 | — | — | EP | disclosed |
| US-4159278-A | PROPHYAXIS, ANTIALLERGENS, SENSITIZATION | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4095028-A | PROPHYLAXIS, ALLERGIES | THE UPJOHN COMPANY (US) | 1978-06-13 | — | — | US | disclosed |
| US-4089973-A | Cyano phenylene dioxamic acid compounds used in the treatment of allergy | THE UPJOHN COMPANY (US) | 1978-05-16 | — | — | US | disclosed |
| US-3993679-A | ANTIALLERGY | THE UPJOHN COMPANY (US) | 1976-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140303152-A1 | BENZOTHIAZINETHIONE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF | TST, SDHA, SDHB | ALDH1A1 389/4885GPR35 3386/4885LMNA 2118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.