SCHEMBL7902280

SCHEMBL7902280

CCCCC(CC)CCC(=O)CCC(C)=O

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA2 P00918 8/20 0.59
CYP3A4 P08684 4/20 0.46
TSHR P16473 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
ATM Q13315 1/20 0.46
ALDH1A1 P00352 5/20 0.45
MAPK1 P28482 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CA1 P00915 3/20 0.37
RECQL P46063 1/20 0.36
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14125872 0.90 CA2 (0.70) CA2CYP3A4TSHRTDP1ATM
SCHEMBL5470163 0.88 CA2 (0.68) CA2CYP3A4TSHRTDP1ATM
SCHEMBL7902949 0.85 LMNA (0.45) CA2MAPTKMT2A
SCHEMBL8834150 0.85 CA2 (0.59) CA2CYP3A4TSHRTDP1ATM
SCHEMBL10892809 0.85 CA2 (0.63) CA2CYP3A4TSHRTDP1ATM
SCHEMBL14125668 0.85 CA2 (0.63) CA2CYP3A4TSHRTDP1ATM
SCHEMBL19085418 0.83 CA2 (0.61) CA2CYP3A4TSHRTDP1ATM
SCHEMBL10380004 0.82 CA2 (0.66) CA2CYP3A4TSHRTDP1ATM
SCHEMBL15731294 0.82 CA2 (0.60) CA2CYP3A4TSHRTDP1ATM
SCHEMBL14628150 0.82 CA2 (0.60) CA2CYP3A4TSHRTDP1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0521650-B1 Working fluid composition for use in refrigeration system KAO CORP (JP) 1997-08-13 EP claimed
US-5401433-A Base oils with ketone groups for use with hydrofluorocarbons, air conditioners KAO CORPORATION (JP) 1995-03-28 US claimed
US-6197211-B1 REFRIGERANT COMPRESSION-TYPE CONTAINING THE REFRIGERANT COMPRISING A HALOGEN-FREE HYDROCARBON OF 2-4 CARBONS AND A REFRIGERATION LUBRICANT COMPRISING, AS A MAIN COMPONENT, A POLYKETONE INCOMPATIBLE WITH THE REFRIGERANT MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2001-03-06 US disclosed
EP-0521650-B1 Working fluid composition for use in refrigeration system KAO CORP (JP) 1997-08-13 EP disclosed
US-5401433-A Base oils with ketone groups for use with hydrofluorocarbons, air conditioners KAO CORPORATION (JP) 1995-03-28 US disclosed
US-5300245-A Mixed with hydrofluorocarbons KAO CORPORATION (JP) 1994-04-05 US disclosed
EP-0521650-A1 Working fluid composition for use in refrigeration system Kao Corporation (JP) 1993-01-07 EP disclosed