SCHEMBL7902949

SCHEMBL7902949

CCCCCCCCC(CCCCCC)CCC(=O)CCC(C)=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.45
MAPT P10636 2/20 0.42
KMT2A Q03164 1/20 0.42
CA2 P00918 3/20 0.42
FFAR1 O14842 2/20 0.42
FFAR4 Q5NUL3 1/20 0.42
GPR84 Q9NQS5 8/20 0.41
LCK P06239 1/20 0.40
PPARD Q03181 1/20 0.40
ZDHHC20 Q5W0Z9 1/20 0.40
ZDHHC2 Q9UIJ5 1/20 0.40
HDAC3 O15379 2/20 0.40
HDAC1 Q13547 2/20 0.40
HDAC2 Q92769 2/20 0.40
HDAC8 Q9BY41 2/20 0.40
HDAC6 Q9UBN7 2/20 0.40
HDAC4 P56524 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15545284 0.88 LMNA (0.52) LMNAMAPTCA2FFAR1FFAR4
SCHEMBL17676338 0.88 LMNA (0.52) LMNAMAPTCA2FFAR1FFAR4
SCHEMBL4622532 0.88 LMNA (0.52) LMNAMAPTCA2FFAR1FFAR4
SCHEMBL17676334 0.88 LMNA (0.52) LMNAMAPTCA2FFAR1FFAR4
SCHEMBL24344117 0.86 KMT2A (0.57) LMNAMAPTKMT2AFFAR1FFAR4
SCHEMBL17676323 0.86 CA2 (0.50) LMNAMAPTCA2FFAR1FFAR4
SCHEMBL7902280 0.85 CA2 (0.59) MAPTKMT2ACA2
SCHEMBL8834147 0.85 LMNA (0.45) LMNAMAPTKMT2ACA2FFAR1
SCHEMBL16023959 0.84 LMNA (0.52) LMNAKMT2AFFAR1FFAR4GPR84
SCHEMBL22602510 0.84 LMNA (0.52) LMNAMAPTCA2FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0521650-B1 Working fluid composition for use in refrigeration system KAO CORP (JP) 1997-08-13 EP claimed
US-5401433-A Base oils with ketone groups for use with hydrofluorocarbons, air conditioners KAO CORPORATION (JP) 1995-03-28 US claimed
US-6197211-B1 REFRIGERANT COMPRESSION-TYPE CONTAINING THE REFRIGERANT COMPRISING A HALOGEN-FREE HYDROCARBON OF 2-4 CARBONS AND A REFRIGERATION LUBRICANT COMPRISING, AS A MAIN COMPONENT, A POLYKETONE INCOMPATIBLE WITH THE REFRIGERANT MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2001-03-06 US disclosed
EP-0521650-B1 Working fluid composition for use in refrigeration system KAO CORP (JP) 1997-08-13 EP disclosed
US-5401433-A Base oils with ketone groups for use with hydrofluorocarbons, air conditioners KAO CORPORATION (JP) 1995-03-28 US disclosed
US-5300245-A Mixed with hydrofluorocarbons KAO CORPORATION (JP) 1994-04-05 US disclosed
EP-0521650-A1 Working fluid composition for use in refrigeration system Kao Corporation (JP) 1993-01-07 EP disclosed