SCHEMBL7902294

SCHEMBL7902294

CCCCc1ccc(P(c2ccc(CCCC)cc2)c2ccc3ccccc3c2-c2c(P(c3ccc(CCCC)cc3)c3ccc(CCCC)cc3)ccc3ccccc23)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
BCHE P06276 2/20 0.37
TRPV1 Q8NER1 1/20 0.37
CA2 P00918 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
DHODH Q02127 1/20 0.36
CTSV O60911 1/20 0.36
CTSL P07711 1/20 0.36
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
HSD11B1 P28845 1/20 0.35
NCEH1 Q6PIU2 1/20 0.35
CNR2 P34972 1/20 0.35
CA1 P00915 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24779295 0.94 TRPV1 (0.36) GAATDP1L3MBTL1BCHETRPV1
SCHEMBL8209092 0.88 HTR2A (0.40) CYP1A2CYP2D6CYP2C19
SCHEMBL15656638 0.85 CNR2 (0.38) BCHETRPV1CA2SMN1; SMN2DHODH
SCHEMBL8203452 0.80 CYP1A2 (0.36) GAATDP1CA2SMN1; SMN2KEAP1
SCHEMBL24272793 0.79 NCEH1 (0.34) GAATDP1L3MBTL1BCHESMN1; SMN2
SCHEMBL8207054 0.79 HTR1B (0.40) GAATDP1L3MBTL1NCEH1
SCHEMBL15658045 0.78 GAA (0.40) GAATDP1L3MBTL1BCHESMN1; SMN2
SCHEMBL29176 0.77 MAPT (0.39) TDP1L3MBTL1CYP1A2ALDH1A1HPGD
SCHEMBL29361524 0.77 MAPT (0.39) TDP1L3MBTL1CYP1A2ALDH1A1HPGD
SCHEMBL146878 0.76 ALDH1A1 (0.44) TDP1CYP1A2ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6197996-B1 ASYMMETRICALLY HYDROGENATING GAMMA-TRIMETHYLAMMONIUM-3-OXABUTANOIC ESTER HALIDE IN PRESENCE OF RUTHENIUM-OPTICALLY ACTIVE PHOSPHINE COMPLEX AS CATALYST, RECOVERING OPTICALLY ACTIVE CARNITINE ESTER FORMED TAKASAGO INTERNATIONAL CORPORATION (JP) 2001-03-06 US disclosed