Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 5/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 3/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | DNTT | P04053 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | POLA1 | P09884 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789233 | 1.00 | TSHR (0.44) | TSHRHPGDTHRBZDHHC20ZDHHC2 | |
| SCHEMBL6917510 | 1.00 | TSHR (0.44) | TSHRHPGDTHRBZDHHC20ZDHHC2 | |
| SCHEMBL2290619 | 0.98 | TSHR (0.46) | TSHRHPGDTHRBZDHHC20ZDHHC2 | |
| SCHEMBL8585258 | 0.93 | TSHR (0.47) | TSHRHPGDTHRBZDHHC20ZDHHC2 | |
| SCHEMBL28389452 | 0.92 | TSHR (0.43) | TSHRHPGDTHRBZDHHC20ZDHHC2 | |
| SCHEMBL1763961 | 0.90 | TSHR (0.37) | TSHRHPGDTHRBZDHHC20ZDHHC2 | |
| SCHEMBL4401693 | 0.87 | TSHR (0.44) | TSHRHPGDTHRBZDHHC20ZDHHC2 | |
| SCHEMBL48742 | 0.86 | TSHR (0.41) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL1648754 | 0.85 | TSHR (0.43) | TSHRHPGDTHRBZDHHC20ZDHHC2 | |
| SCHEMBL29117687 | 0.85 | TSHR (0.43) | TSHRHPGDTHRBZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5372881-A | Laminate with paintability and scratch resistance; nitrile and unsaturated ester copolymer layers | ALLIEDSIGNAL INC. (US) | 1994-12-13 | — | — | US | claimed |
| US-20150158644-A1 | MULTILAYER FILMS FORMED USING PRIMER COMPOSITIONS AND METHODS FOR MANUFACTURING THE SAME | HONEYWELL INTERNATIONAL INC. | 2015-06-11 | — | — | US | disclosed |
| US-20120219767-A1 | FLUOROPOLYMER FILMS AND METHODS FOR MAKING THE SAME | HONEYWELL INTERNATIONAL INC. (US) | 2012-08-30 | — | — | US | disclosed |
| WO-2012116140-A2 | FLUOROPOLYMER FILMS AND METHODS FOR MAKING THE SAME | HONEYWELL INTERNATIONAL INC. (US) | 2012-08-30 | — | — | WO | disclosed |
| WO-2012037180-A1 | COEXTRUDED MULTILAYER FILM STRUCTURE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| US-7070675-B2 | Fluoropolymer film structures and laminates produced therefrom | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-07-04 | — | — | US | disclosed |
| EP-1131375-B1 | FLUOROPOLYMER FILM STRUCTURES AND LAMINATES PRODUCED THEREFROM | DU PONT (US) | 2004-03-03 | — | — | EP | disclosed |
| US-20030203190-A1 | Fluoropolymer film structures and laminates produced therefrom | SCHMIDT JAMES JOHN (US) | 2003-10-30 | — | — | US | disclosed |
| US-6632518-B1 | Primer layer of an amine functional acrylic polymer, thermoplastic adhesive layer containing acid modified polyolefin, thermoplastic substrate | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-10-14 | — | — | US | disclosed |
| EP-1131375-A1 | FLUOROPOLYMER FILM STRUCTURES AND LAMINATES PRODUCED THEREFROM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000022032-A1 | FLUOROPOLYMER FILM STRUCTURES AND LAMINATES PRODUCED THEREFROM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-04-20 | — | — | WO | disclosed |
| EP-0598822-B1 | MULTILAYER FILM CONSTRUCTIONS | ALLIED SIGNAL INC (US) | 1997-10-08 | — | — | EP | disclosed |
| US-5372881-A | Laminate with paintability and scratch resistance; nitrile and unsaturated ester copolymer layers | ALLIEDSIGNAL INC. (US) | 1994-12-13 | — | — | US | disclosed |
| EP-0598822-A1 | MULTILAYER FILM CONSTRUCTIONS. | ALLIED SIGNAL INC (US) | 1994-06-01 | — | — | EP | disclosed |
| WO-1993003922-A1 | MULTILAYER FILM CONSTRUCTIONS | ALLIED-SIGNAL INC. (US) | 1993-03-04 | — | — | WO | disclosed |
| US-5139878-A | Fluoropolymer, thermoplastic polymer, adhesive layer; high adhesive strength, moisture and gas barriers | ALLIED-SIGNAL INC. (US) | 1992-08-18 | — | — | US | disclosed |