Thymine

Thymine

SCHEMBL7902560

C1CCC1.Cc1c[nH]c(=O)[nH]c1=O

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ATAD2 Q6PL18 1/20 0.86
MAPT P10636 3/20 0.50
KDM4C Q9H3R0 1/20 0.50
GAA P10253 3/20 0.47
DPYD Q12882 4/20 0.46
ALDH1A1 P00352 2/20 0.46
LMNA P02545 1/20 0.46
CYP19A1 P11511 1/20 0.46
TSHR P16473 1/20 0.46
THPO P40225 1/20 0.46
MTOR P42345 1/20 0.46
HTT P42858 1/20 0.46
HBB P68871 1/20 0.46
PMP22 Q01453 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thymine SCHEMBL750450 0.93 ATAD2 (1.00) ATAD2MAPTKDM4CGAADPYD
Thymine SCHEMBL15323914 0.93 ATAD2 (1.00) ATAD2MAPTKDM4CGAADPYD
Thymine SCHEMBL17201833 0.93 ATAD2 (1.00) ATAD2MAPTKDM4CGAADPYD
Thymine SCHEMBL29669526 0.93
Thymine SCHEMBL5235 0.93
Thymine SCHEMBL4811815 0.91
Thymine SCHEMBL5176783 0.91 ATAD2 (0.95) ATAD2MAPTKDM4CGAADPYD
Thymine SCHEMBL935833 0.91 ATAD2 (0.95) ATAD2MAPTKDM4CGAADPYD
Thymine SCHEMBL3500839 0.91 ATAD2 (0.95) ATAD2MAPTKDM4CGAADPYD
Thymine SCHEMBL31403209 0.91 ATAD2 (0.95) ATAD2MAPTKDM4CGAADPYD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3697930-B1 PRIMER-INDEPENDENT DNA POLYMERASES AND THEIR USE FOR DNA SYNTHESIS CONSEJO SUPERIOR INVESTIGACION (ES) 2023-07-12 EP disclosed
EP-3697930-A1 PRIMER-INDEPENDENT DNA POLYMERASES AND THEIR USE FOR DNA SYNTHESIS Agencia Consejo Superior De Investigaciones Cientificas (ES) 2020-08-26 EP disclosed
US-20200263151-A1 PRIMER-INDEPENDENT DNA POLYMERASES AND THEIR USE FOR DNA SYNTHESIS INSTITUT PASTEUR (FR) 2020-08-20 US disclosed
WO-2019077119-A1 PRIMER-INDEPENDENT DNA POLYMERASES AND THEIR USE FOR DNA SYNTHESIS CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) 2019-04-25 WO disclosed
US-10124312-B2 Method for direct photopatterning of molecules on surfaces THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-11-13 US disclosed
US-9931634-B2 High throughput DNA damage quantification of human tissue with home-based collection device THE REGENTS OF THE UNIVERISTY OF CALIFORNIA (US) 2018-04-03 US disclosed
US-20160025709-A1 HIGH THROUGHPUT DNA DAMAGE QUANTIFICATION OF HUMAN TISSUE WITH HOME-BASED COLLECTION DEVICE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2016-01-28 US disclosed
US-20150343413-A1 METHOD FOR DIRECT PHOTOPATTERNING OF MOLECULES ON SURFACES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2015-12-03 US disclosed
WO-2000047600-A9 PHOTO-INDUCED NUCLEIC ACID HYBRIDIZATION UNIV MARYLAND (US) 2001-09-13 WO disclosed
US-6150663-A Food Sanitizing apparatus ROSENTHAL RICHARD A (US) 2000-11-21 US disclosed
WO-2000047600-A1 PHOTO-INDUCED NUCLEIC ACID HYBRIDIZATION UNIVERSITY OF MARYLAND (US) 2000-08-17 WO disclosed
US-6010727-A Actinic process for cold pasteurization of fresh foods and beverages PURELIGHT TECHNOLOGIES, LLC 2000-01-04 US disclosed
US-6006659-A Personal pasteurization system ROSENTHAL RICHARD A (US) 1999-12-28 US disclosed
US-5314817-A Hapten modified with pyrimidine dimer or benzylammonium group, useful in reactions of proteins, nucleic acids and carbohydrates THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1994-05-24 US disclosed
US-5302516-A Polypeptides having a binding site specific for a reactant and having an active functionality near that site to promote or catalyze the reaction; kinetics REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1994-04-12 US disclosed
US-5215889-A CATALYTIC AND REACTIVE POLYPEPTIDES AND METHODS FOR THEIR PREPARATION AND USE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1993-06-01 US disclosed
EP-0445214-A4 CATALYTIC AND REACTIVE POLYPEPTIDES AND METHODS FOR THEIR PREPARATION AND USE 1991-11-13 EP disclosed
EP-0445214-A1 CATALYTIC AND REACTIVE ANTIBODIES AND ANTIBODY FRAGMENTS AND METHODS FOR THEIR PREPARATION AND USE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1991-09-11 EP disclosed
WO-1990005746-A1 CATALYTIC AND REACTIVE POLYPEPTIDES AND METHODS FOR THEIR PREPARATION AND USE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1990-05-31 WO disclosed