Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 11/20 | 0.39 |
| ▸ | CACNB4 | O00305 | 4/20 | 0.38 |
| ▸ | CACNA1A | O00555 | 4/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.38 |
| ▸ | CACNG3 | O60359 | 4/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7911306 | 0.87 | KDM4E (0.48) | KDM4EPOLBALDH1A1ACHECACNB4 | |
| SCHEMBL7916819 | 0.79 | ACHE (0.38) | KDM4EALDH1A1ACHECACNB4CACNA1A | |
| SCHEMBL7910360 | 0.74 | PRNP (0.42) | PRNPPPARGHTTNCOA2NPSR1 | |
| SCHEMBL6609247 | 0.67 | HPGD (0.40) | PRNPPPARGHTTNCOA2NPSR1 | |
| SCHEMBL13104836 | 0.67 | ACHE (0.57) | KDM4EPOLBALDH1A1MAPK1ACHE | |
| SCHEMBL26310824 | 0.66 | KDM4E (0.37) | NPSR1KDM4EL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL26967933 | 0.65 | P2RX3 (0.39) | NPSR1KDM4EPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL30843853 | 0.65 | P2RX3 (0.39) | NPSR1KDM4EPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL29338978 | 0.65 | KDM4E (0.57) | KDM4EALDH1A1MAPK1ACHEBCHE | |
| SCHEMBL6208465 | 0.64 | KDM4E (0.38) | PRNPPPARGHTTNCOA2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |