Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.39 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.39 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916774 | 0.83 | CACNB4 (0.54) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL7911213 | 0.80 | CACNB4 (0.37) | NPSR1POLBKDM4ECACNB4CACNA1A | |
| SCHEMBL7902853 | 0.74 | PRNP (0.44) | PRNPPPARGHTTNCOA2NPSR1 | |
| SCHEMBL6956277 | 0.68 | ACHE (0.40) | NPSR1KDM4EALDH1A1TSHRMAPK1 | |
| SCHEMBL3556897 | 0.67 | MAPT (0.40) | HTTPOLBL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL29338978 | 0.66 | KDM4E (0.57) | KDM4EALDH1A1MAPK1ACHEKMT2A | |
| SCHEMBL11614853 | 0.66 | TDP1 (0.39) | HTTPOLBL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL6701780 | 0.66 | ACHE (0.40) | NPSR1KDM4EALDH1A1TSHRMAPK1 | |
| SCHEMBL9633216 | 0.65 | ACHE (0.69) | RXFP1POLBL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL4507172 | 0.65 | POLB (0.42) | POLBL3MBTL1ALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |