Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7855792 | 0.84 | TP53 (0.36) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL937606 | 0.83 | TP53 (0.35) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL1764669 | 0.82 | TSHR (0.38) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL7098338 | 0.78 | TP53 (0.39) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL28063692 | 0.77 | SMN1; SMN2 (0.50) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL11606729 | 0.73 | TSHR (0.40) | — | |
| SCHEMBL7894304 | 0.72 | TP53 (0.34) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL6157607 | 0.70 | TP53 (0.30) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL1004018 | 0.68 | CYP3A4 (0.59) | CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL28035980 | 0.67 | CYP3A4 (0.47) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137617-A1 | METHOD OF MAKING ALPHA-CHLORO-ALPHA-ALPHA-DIFLUORO AROMATIC COMPOUNDS | OCCIDENTAL CHEMICAL CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| US-6222078-B1 | REACTNG TRICHLORO AROMATIC COMPOUND WITH HYDROGEN FLUORIDE IN PRESENCE OF METAL OXIDE CATLYST OR METAL COMPOUND CATALYST TO FORM CHLORO, DIFLUORO AROMATIC COMPOUND | OCCIDENTAL CHEMICAL CORPORATION | 2001-04-24 | — | — | US | disclosed |
| WO-2000034215-A1 | METHOD OF MAKING α-CHLORO-α,α-DIFLUORO AROMATIC COMPOUNDS | OCCIDENTAL CHEMICAL CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |