SCHEMBL1764669

SCHEMBL1764669

Cc1c(Cl)cc(C(Cl)(Cl)Cl)c(Cl)c1Cl

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
CYP3A4 P08684 1/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TP53 P04637 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HIF1A Q16665 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7098338 0.82 TP53 (0.39) CYP3A4TP53CYP2C9CYP2C19SMN1; SMN2
SCHEMBL7903146 0.82 TP53 (0.35) TP53CYP2C9CYP2C19SMN1; SMN2HIF1A
SCHEMBL937606 0.82 TP53 (0.35) TP53CYP2C9CYP2C19SMN1; SMN2HIF1A
SCHEMBL28063692 0.81 SMN1; SMN2 (0.50) TP53CYP2C9CYP2C19SMN1; SMN2HIF1A
SCHEMBL1833205 0.81 CYP3A4 (0.38) TSHRCYP3A4MAPK1TDP1TP53
SCHEMBL7855792 0.79 TP53 (0.36) TP53CYP2C9CYP2C19SMN1; SMN2HIF1A
SCHEMBL6417699 0.77 CYP3A4 (0.53) TSHRCYP3A4MAPK1TDP1
SCHEMBL11553083 0.73 CYP3A4 (0.42) TSHRCYP3A4MAPK1TDP1
SCHEMBL6157607 0.73 TP53 (0.30) TP53CYP2C9CYP2C19SMN1; SMN2HIF1A
SCHEMBL10493668 0.73 CYP3A4 (0.35) TSHRCYP3A4MAPK1TDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240279396-A1 CYCLIC OLIGO(ARYLENE ETHER)S, PROCESSES FOR THEIR PREPARATION AND THEIR USE SOLVAY SA (BE) 2024-08-22 US claimed
EP-4352045-A1 CYCLIC OLIGO(ARYLENE ETHER)S, PROCESSES FOR THEIR PREPARATION AND THEIR USE SYENSQO SA (BE) 2024-04-17 EP claimed
CN-115304748-B Preparation method of porous polymer material 沈阳师范大学 2023-06-23 CN claimed
WO-2022258332-A1 CYCLIC OLIGO(ARYLENE ETHER)S, PROCESSES FOR THEIR PREPARATION AND THEIR USE SOLVAY SA (BE) 2022-12-15 WO claimed
CN-115304748-A Preparation method of porous polymer material 沈阳师范大学 2022-11-08 CN claimed
CN-113247866-B Method and equipment for extracting insoluble sulfur 山东阳谷华泰化工股份有限公司 2022-08-26 CN claimed
CN-113956016-A Nano-permeation crystallization self-healing inorganic waterproof material on back water surface and preparation method thereof 朱耀台 2022-01-21 CN claimed
CN-113648686-A Defoaming agent for oil exploitation and processing system and processing method thereof 哈尔滨艾拓普科技有限公司 2021-11-16 CN claimed
CN-113247866-A Extraction method and equipment for insoluble sulfur 山东阳谷华泰化工股份有限公司 2021-08-13 CN claimed
CN-109888196-B Porous sulfur/carbon composite material, preparation method thereof and application of porous sulfur/carbon composite material in lithium-sulfur battery 中国科学院大连化学物理研究所 2021-06-22 CN claimed
US-5936029-A VULCANIZABLE ELASTOMER; TIRES BRIDGESTONE CORPORATION (JP) 1999-08-10 US claimed
WO-1999035111-A1 PROCESS FOR PREPARATION OF TFPX-DICHLORIDE ALPHA METALS, INC. (US) 1999-07-15 WO claimed
EP-0841347-A1 Synthesis of macrocyclic polymers with group IIA and IIB metal cyclic organometallic initiators Bridgestone Corporation (JP) 1998-05-13 EP claimed
EP-0841368-A1 Synthesis of macrocyclic polymers having low hysteresis compounded properties Bridgestone Corporation (JP) 1998-05-13 EP claimed
US-5700888-A ANIONIC POLYMERS; VULCANIZABLE ELASTOMERS; CYCLIC ORGANOMETALLIC COMPOUND AS PROMOTERS BRIDGESTONE CORPORATION (JP) 1997-12-23 US claimed
US-5677399-A POLYMERIZATION OF THE MONOMERS BY ADDITION INTO THE INITIATOR RING AT THE BOND BETWEEN THE ATOMS AND ITS TWO ADJUSCENT CARBON ATOMS, METAL ACTS AS A BRIDGE BETWEEN TWO LIVING ENDS OF PROPOGATION CHAIN, AND COUPLING OF LIVING ENDS BRIDGESTONE CORPORATION (JP) 1997-10-14 US claimed
US-5235023-A Forming polybenzimidazoles, polybenzthiazoles and polybenz-oxazoles; disodium or dilithium terephthalate monomer THE DOW CHEMICAL COMPANY (US) 1993-08-10 US claimed
US-5069943-A Process for producing modified molded polymer article HERCULES INCORPORATED (US) 1991-12-03 US claimed
EP-0449811-A1 IMPROVED PROCESS FOR SYNTHESIS OF HETEROCYCLIC POLYMERS THE DOW CHEMICAL COMPANY (US) 1991-10-09 EP claimed
WO-1990006960-A1 IMPROVED PROCESS FOR SYNTHESIS OF HETEROCYCLIC POLYMERS THE DOW CHEMICAL COMPANY (US) 1990-06-28 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240279396-A1 CYCLIC OLIGO(ARYLENE ETHER)S, PROCESSES FOR THEIR PREPARATION AND THEIR USE PDXK, HCK, DEK TSHR 3110/4885CYP3A4 199/4885MAPK1 1246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.