Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11658812 | 0.83 | CYP3A4 (0.36) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL11523387 | 0.83 | TP53 (0.35) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL1764669 | 0.82 | TSHR (0.38) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL7903146 | 0.78 | TP53 (0.35) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL937606 | 0.78 | TP53 (0.35) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL28063692 | 0.77 | SMN1; SMN2 (0.50) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL7855792 | 0.76 | TP53 (0.36) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL6157607 | 0.70 | TP53 (0.30) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL10488673 | 0.68 | SMN1; SMN2 (0.65) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL1004018 | 0.68 | CYP3A4 (0.59) | CYP2C19SMN1; SMN2HIF1AARCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610813-B2 | Low number of hydrogen-carbon bonds; for example polyester derived from 2,3,5,6-tetrachloro-p-xylylene glycol and chlorendic acid; use as waveguide core and/or cladding material in optical fibers and optical devices | CORNING INCORPORATED | 2003-08-26 | — | — | US | disclosed |
| US-20030013833-A1 | Highly-halogenated low optical loss polymer | HORN KEITH A (US) | 2003-01-16 | — | — | US | disclosed |
| US-6470131-B1 | A POLYESTER, POLYLACTONE OR POLYCARBONATE HAVING LESS THAN 50 HYDROGEN-CARBON BONDS PER 1000 MOLECULAR WEIGHT UNITS USED AS WAVEGUIDE CORE MATERIAL AND/OR A WAVEGUIDE CLADDING MATERIAL IN OPTICAL FIBERS AND/OR PLANAR OPTICAL DEVICES. | CORNING INCORPORATED | 2002-10-22 | — | — | US | disclosed |
| WO-2002036659-A2 | HIGHLY-HALOGENATED LOW OPTICAL LOSS POLYESTER | CORNING INCORPORATED (US) | 2002-05-10 | — | — | WO | disclosed |
| US-4141912-A | Process for the preparation of polyhalobenzylic disulfooxonium compounds | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1979-02-27 | — | — | US | disclosed |
| US-4075238-A | Polyhalobenzylic disulfooxonium compounds | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |