Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19867567 | 0.83 | LMNA (0.50) | CASP1SLC6A2SLC6A4SLC6A3L3MBTL1 | |
| SCHEMBL7903235 | 0.83 | BRD4 (0.52) | BRD4CREBBPTP53CYP3A4ALDH1A1 | |
| SCHEMBL11605502 | 0.77 | TP53 (0.53) | TP53CYP3A4ALDH1A1L3MBTL1LMNA | |
| SCHEMBL6222759 | 0.77 | TP53 (0.53) | TP53CYP3A4ALDH1A1L3MBTL1LMNA | |
| SCHEMBL11605997 | 0.76 | ALDH1A1 (0.53) | BRD4CREBBPTP53CYP3A4ALDH1A1 | |
| SCHEMBL23428912 | 0.76 | ACP3 (0.42) | CYP3A4ALDH1A1CASP1SLC6A2SLC6A4 | |
| SCHEMBL6055352 | 0.76 | TP53 (0.52) | BRD4CREBBPTP53CYP3A4ALDH1A1 | |
| SCHEMBL6055217 | 0.74 | ALDH1A1 (0.51) | TP53CYP3A4ALDH1A1L3MBTL1LMNA | |
| SCHEMBL7330851 | 0.74 | TP53 (0.50) | BRD4CREBBPTP53CYP3A4ALDH1A1 | |
| SCHEMBL6055172 | 0.74 | LMNA (0.52) | TP53CYP3A4ALDH1A1ALOX5L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291485-B1 | TREATMENT OF POST-PTCA RESTENOSIS | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-1002797-A1 | 4,5-DIHYDRO- 1H]-BENZ g]INDAZOLE-3-CARBOXYLIC ACID DERIVATIVES | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2000-05-24 | — | — | EP | disclosed |