Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.52 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11605997 | 0.86 | ALDH1A1 (0.53) | BRD4CREBBPALDH1A1TP53CYP3A4 | |
| SCHEMBL11420513 | 0.84 | LTA4H (0.57) | BRD4CREBBPALDH1A1CYP3A4LTA4H | |
| SCHEMBL6222759 | 0.84 | TP53 (0.53) | ALDH1A1TP53CYP3A4LTA4HLMNA | |
| SCHEMBL11605502 | 0.84 | TP53 (0.53) | ALDH1A1TP53CYP3A4LTA4HLMNA | |
| SCHEMBL7903229 | 0.83 | BRD4 (0.43) | BRD4CREBBPALDH1A1TP53CYP3A4 | |
| SCHEMBL6055352 | 0.82 | TP53 (0.52) | BRD4CREBBPALDH1A1TP53CYP3A4 | |
| SCHEMBL477599 | 0.81 | SMN1; SMN2 (0.62) | LMNAMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6055172 | 0.81 | LMNA (0.52) | ALDH1A1TP53CYP3A4LMNAMAPK1 | |
| SCHEMBL12251553 | 0.81 | ALDH1A1 (0.51) | ALDH1A1TP53CYP3A4LTA4HLMNA | |
| SCHEMBL6055217 | 0.81 | ALDH1A1 (0.51) | ALDH1A1TP53CYP3A4LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291485-B1 | TREATMENT OF POST-PTCA RESTENOSIS | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-1002797-A1 | 4,5-DIHYDRO- 1H]-BENZ g]INDAZOLE-3-CARBOXYLIC ACID DERIVATIVES | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2000-05-24 | — | — | EP | disclosed |
| US-4208536-A | PROMOTERS COMPRISING AROMATIC ALDEHYDES OR ACETALS OR A BENZOHYDROL | RHONE-POULENC INDUSTRIES (FR) | 1980-06-17 | — | — | US | disclosed |