Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.34 |
| ▸ | CDC25B | P30305 | 4/20 | 0.34 |
| ▸ | FGF1 | P05230 | 2/20 | 0.34 |
| ▸ | FGF2 | P09038 | 2/20 | 0.34 |
| ▸ | VEGFA | P15692 | 2/20 | 0.34 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15654185 | 0.88 | BCHE (0.44) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL1034642 | 0.88 | BCHE (0.44) | SSTR5PDPK1MTORBCHEALOX15 | |
| SCHEMBL2804927 | 0.88 | ALDH1A1 (0.38) | PDPK1MTORBCHEALOX15ALDH1A1 | |
| SCHEMBL7775231 | 0.87 | PDPK1 (0.45) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL1775905 | 0.87 | GJB2 (0.46) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL1775228 | 0.87 | GJB2 (0.46) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL1775230 | 0.87 | GJB2 (0.46) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL1742927 | 0.86 | BCHE (0.44) | SSTR5PDPK1MTORBCHEALOX15 | |
| SCHEMBL5490746 | 0.86 | BCHE (0.44) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL8814352 | 0.84 | BCHE (0.43) | SSTR1SSTR2SSTR4SSTR3SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0642799-B1 | Improved prodrugs for enzyme mediated activation | HOECHST AG (DE) | 2001-11-07 | — | — | EP | disclosed |
| US-5621002-A | HAVING A MODIFIED COMPETITIVE ENZYME ACTIVITY INHBITOR LINKED TO A SPACER-DRUG; ENZYME CLEAVAGE AT A LOWER CONCENTRATION, I.E. LOW MICHAELIS-MENTEN CONSTANT(KM) | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1997-04-15 | — | — | US | disclosed |
| EP-0642799-A1 | Improved prodrugs for enzyme mediated activation | BEHRINGWERKE Aktiengesellschaft (DE) | 1995-03-15 | — | — | EP | disclosed |