SCHEMBL7903533

SCHEMBL7903533

C#CC(C)(CCCc1ccc(F)c(Oc2ccccc2)c1)c1ccc(OCC)cc1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.39
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
PPARG P37231 1/20 0.35
LPAR1 Q92633 4/20 0.34
LPAR5 Q9H1C0 4/20 0.34
TDP1 Q9NUW8 1/20 0.34
CACNA1C Q13936 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
KIF11 P52732 1/20 0.33
KAT6A Q92794 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10647356 0.93 LTA4H (0.41) LTA4HPPARGLPAR1LPAR5
SCHEMBL10653711 0.93 MAPT (0.38) LMNAMAPTATML3MBTL1CACNA1C
SCHEMBL10649266 0.93 CACNA1C (0.38) LMNAMAPTATML3MBTL1PPARG
SCHEMBL10651950 0.92 LTA4H (0.38) LTA4HPPARGLPAR1LPAR5KAT6A
SCHEMBL10650211 0.92 MAPT (0.37) LMNAMAPTATML3MBTL1CACNA1C
SCHEMBL10651943 0.92 MAPT (0.38) LMNAMAPTATML3MBTL1PPARG
SCHEMBL10647519 0.92 MAPT (0.37) LMNAMAPTATML3MBTL1LPAR1
SCHEMBL10652621 0.92 MAPT (0.44) LMNAMAPTATML3MBTL1PPARG
SCHEMBL10649304 0.91 L3MBTL1 (0.36) LTA4HL3MBTL1LPAR1LPAR5CACNA1C
SCHEMBL10651741 0.91 KIF11 (0.35) LPAR1LPAR5KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0771526-A2 Pesticidal compositions containing 4-bromo-2-(4-chlorophenyl)-1-ethoxymethyl-4-trifluoromethylpyrrole-3-carbonitrile and pyrethroids SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-05-07 EP claimed
JP-9301810-A None JP disclosed
US-6201008-B1 4-BROMO-2-(4-CHLOROPHENYL)-1-ETHOXYMETHYL-5-TRIFLUOROMETHYLPYR ROLE-3-CARBONITRILE SYNERGISTIC MIXTURE WITH PYRETHYROIDAL COMPOUND SUMITOMO CHEMICAL CO. LTD. (JP) 2001-03-13 US disclosed
US-5965602-A SYNERGISTIC MIXTURE OF PERMETHRIN AND 4-BROMO-2-(4-CHLOROPHENYL)-1-ETHOXYMETHYL-5-TRIFLUOROMETHYL-PY RROLE-3-CARBONITRILE SUMITOMO CHEMICAL COMPANY LTD. (JP) 1999-10-12 US disclosed
JP-H09301810-A INSECTICIDAL COMPOSITION SUMITOMO CHEM CO LTD 1997-11-25 JP disclosed
EP-0771526-A2 Pesticidal compositions containing 4-bromo-2-(4-chlorophenyl)-1-ethoxymethyl-4-trifluoromethylpyrrole-3-carbonitrile and pyrethroids SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-05-07 EP disclosed
EP-0193189-B1 NOVEL COMPOUND, ITS PRODUCTION AND INSECTICIDAL AND ACARICIDAL COMPOSITION CONTAINING IT AS AN ACTIVE INGREDIENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-09-28 EP disclosed
US-4772633-A 6-pyridyl- and 6-phenyl-3-phenyl-1-hexenes and -1-hexynes, composition containing them, and insecticidal and acaricidal method of using them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-09-20 US disclosed
EP-0193189-A1 Novel compound, its production and insecticidal and acaricidal composition containing it as an active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-09-03 EP disclosed