Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 7/20 | 0.75 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8468925 | 1.00 | DNM1 (0.75) | DNM1TSHRALDH1A1THRBCA12 | |
| SCHEMBL8467869 | 1.00 | DNM1 (0.75) | DNM1TSHRALDH1A1THRBCA12 | |
| SCHEMBL7895664 | 1.00 | DNM1 (0.75) | DNM1TSHRALDH1A1THRBCA12 | |
| SCHEMBL3307838 | 1.00 | DNM1 (0.75) | DNM1TSHRALDH1A1THRBCA12 | |
| SCHEMBL7904773 | 0.95 | DNM1 (0.75) | DNM1TSHRALDH1A1THRBCA12 | |
| SCHEMBL29175288 | 0.95 | DNM1 (0.75) | DNM1TSHRALDH1A1THRBCA12 | |
| SCHEMBL7903172 | 0.95 | DNM1 (0.75) | DNM1TSHRALDH1A1THRBCA12 | |
| Bromoethane SCHEMBL14840431 | 0.90 | DNM1 (0.83) | DNM1TSHRALDH1A1THRBCA12 | |
| SCHEMBL1650408 | 0.89 | ALDH1A1 (0.69) | DNM1TSHRALDH1A1CA12CA2 | |
| Dymanthine SCHEMBL7895663 | 0.87 | DNM1 (0.62) | DNM1TSHRALDH1A1THRBS1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1094801-A2 | POLY(DIALLYLAMINE)-BASED BILE ACID SEQUESTRANTS | GELTEX PHARMACEUTICALS, INC. (US) | 2001-05-02 | — | — | EP | disclosed |
| WO-1998029107-A2 | POLY(DIALLYLAMINE)-BASED BILE ACID SEQUESTRANTS | GELTEX PHARMACEUTICALS, INC. (US) | 1998-07-09 | — | — | WO | disclosed |