Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 4/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.35 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11993969 | 0.81 | PIK3CA (0.41) | POLBL3MBTL1PIK3CAALDH1A1LMNA | |
| SCHEMBL31341824 | 0.80 | PIK3CA (0.37) | POLBL3MBTL1PIK3CAALDH1A1LMNA | |
| SCHEMBL22833476 | 0.80 | PIK3CA (0.37) | POLBL3MBTL1PIK3CAALDH1A1LMNA | |
| SCHEMBL38665916 | 0.79 | PIK3CA (0.41) | POLBPIK3CAALDH1A1MAPTCASP1 | |
| SCHEMBL215544 | 0.79 | PIK3CA (0.41) | POLBPIK3CAALDH1A1MAPTCASP1 | |
| SCHEMBL24565639 | 0.78 | POLB (0.44) | POLBL3MBTL1PIK3CAALDH1A1MAPT | |
| SCHEMBL19483221 | 0.78 | MBOAT4 (0.34) | POLBL3MBTL1ALDH1A1LMNAHPGD | |
| SCHEMBL13299148 | 0.76 | LMNA (0.42) | POLBL3MBTL1ALDH1A1LMNAHPGD | |
| SCHEMBL33961 | 0.75 | MAPT (0.44) | POLBL3MBTL1PIK3CAALDH1A1MAPT | |
| SCHEMBL4864975 | 0.75 | MAPT (0.44) | POLBL3MBTL1PIK3CAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |