Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904260 | 1.00 | PTGES2 (0.47) | PTGES2LMNAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL7905095 | 0.93 | PTGES2 (0.50) | PTGES2LMNAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL7905094 | 0.93 | PTGES2 (0.50) | PTGES2LMNAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL5572462 | 0.82 | TLR9 (0.64) | LMNAALDH1A1L3MBTL1EGFRTLR9 | |
| SCHEMBL29149692 | 0.82 | TLR9 (0.64) | LMNAALDH1A1L3MBTL1EGFRTLR9 | |
| SCHEMBL5572469 | 0.82 | TLR9 (0.64) | LMNAALDH1A1L3MBTL1EGFRTLR9 | |
| SCHEMBL31490949 | 0.80 | ALDH1A1 (0.60) | PTGES2LMNAMAPTALDH1A1FBP1 | |
| SCHEMBL942513 | 0.77 | TLR9 (0.64) | LMNAMAPTALDH1A1EGFRTLR9 | |
| SCHEMBL7905290 | 0.77 | TLR9 (0.64) | LMNAMAPTALDH1A1EGFRTLR9 | |
| SCHEMBL7896098 | 0.77 | NFE2L2 (0.61) | LMNAALDH1A1EGFRTLR9NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201131-B1 | REACTING A 2-(ARYLSUFONYL) ETHANOL DERIVATIVE WITH AN ACID ANHYDRIDE IN PRESENCE OF A BASE, FURTHER REACTING THIS WITH AN AROMATIC HALIDE IN THE PRESENCE OF A PALLADIUM CATALYST; USEFUL AS INTERMEDIATES TO DRUGS, AGROCHEMICALS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-03-13 | — | — | US | disclosed |