Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904534 | 0.86 | PKM (0.45) | PKMPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL7906423 | 0.85 | CYP2C9 (0.44) | PKMPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL7903086 | 0.85 | CYP2C9 (0.44) | PKMPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL7904340 | 0.85 | ALDH1A1 (0.60) | PKMHTTALDH1A1KMT2AGAA | |
| SCHEMBL4635004 | 0.75 | PKM (0.56) | PKMHTTPOLBALDH1A1MEN1 | |
| SCHEMBL12330364 | 0.73 | PKM (0.61) | PKMHTTPOLBALDH1A1MEN1 | |
| SCHEMBL29657316 | 0.73 | PKM (0.61) | PKMHTTPOLBALDH1A1MEN1 | |
| SCHEMBL16019510 | 0.73 | MEN1 (0.62) | PKMHTTPOLBALDH1A1MEN1 | |
| SCHEMBL31629999 | 0.73 | PKM (0.61) | PKMHTTPOLBALDH1A1MEN1 | |
| SCHEMBL31554265 | 0.72 | POLB (0.58) | PKMHTTPOLBALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194438-B1 | ANTITUMOR AGENTS; ANTICANCER AGENTS; FARNESYL-PROTEIN TRANSFERASE INHIBITOR | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| EP-1006113-A1 | Derivatives of 2-(2-oxo-ethylidene)-imidazolidin-4-one and their use to inhibit abnormal cell growth | Pfizer Products Inc. (US) | 2000-06-07 | — | — | EP | disclosed |