Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905726 | 0.99 | FLT3 (0.40) | FLT3USP2POLBL3MBTL1KDM4E | |
| SCHEMBL7904730 | 0.96 | FLT3 (0.40) | FLT3USP2POLBL3MBTL1KDM4E | |
| SCHEMBL7908577 | 0.95 | FLT3 (0.39) | FLT3USP2POLBL3MBTL1KDM4E | |
| SCHEMBL7896411 | 0.93 | USP2 (0.43) | FLT3USP2POLBL3MBTL1KDM4E | |
| SCHEMBL7903980 | 0.86 | FLT3 (0.35) | FLT3USP2POLBL3MBTL1KDM4E | |
| SCHEMBL7896514 | 0.85 | HRH3 (0.42) | POLBL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL7908450 | 0.85 | HRH3 (0.43) | POLBL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL7904663 | 0.84 | MEN1 (0.35) | FLT3USP2POLBL3MBTL1KDM4E | |
| SCHEMBL7908545 | 0.84 | PRKDC (0.39) | FLT3USP2POLBL3MBTL1KDM4E | |
| SCHEMBL7908490 | 0.83 | FLT3 (0.42) | FLT3USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |