Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 4/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904730 | 0.98 | FLT3 (0.40) | FLT3CYP2D6PRKDCABL1KDM4E | |
| SCHEMBL7904450 | 0.95 | FLT3 (0.40) | FLT3PRKDCKDM4EPOLBL3MBTL1 | |
| SCHEMBL7905726 | 0.95 | FLT3 (0.40) | FLT3ABL1KDM4EPOLBL3MBTL1 | |
| SCHEMBL7896411 | 0.91 | USP2 (0.43) | FLT3CYP2D6KDM4ECYP1A2POLB | |
| SCHEMBL7903980 | 0.89 | FLT3 (0.35) | FLT3CYP2D6ABL1KDM4ECYP1A2 | |
| SCHEMBL7905773 | 0.85 | BACE1 (0.39) | FLT3CYP2D6PRKDCABL1KDM4E | |
| SCHEMBL7908545 | 0.85 | PRKDC (0.39) | FLT3CYP2D6PRKDCABL1KDM4E | |
| SCHEMBL7908490 | 0.85 | FLT3 (0.42) | FLT3CYP1A2LMNABACE1USP2 | |
| SCHEMBL7896514 | 0.83 | HRH3 (0.42) | CYP2D6KDM4EPOLBL3MBTL1LMNA | |
| SCHEMBL7908450 | 0.83 | HRH3 (0.43) | CYP2D6KDM4EPOLBL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |