Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7637941 | 0.83 | GAA (0.48) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL7594773 | 0.79 | MAPT (0.52) | MAPTKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL7599729 | 0.79 | RAB9A (0.51) | MAPTKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL7641142 | 0.77 | NPC1 (0.58) | MAPTKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL7642827 | 0.77 | ALDH1A1 (0.53) | MAPTKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL22289851 | 0.75 | MAPT (0.74) | MAPTKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL7915018 | 0.75 | LMNA (0.48) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL7661828 | 0.74 | TACR1 (0.39) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL22274806 | 0.73 | MAPT (0.71) | MAPTKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL6815484 | 0.73 | MAPT (0.71) | MAPTKMT2AMEN1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207715-B1 | USEFUL IN THERAPY OF DISEASES ASSOCIATED WITH HERPES VIRUSES INCLUDING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, VARICELLA-ZOSTER VIRUS, HUMAN HERPESVIRUSES-6 AND -7, AND KAPOSI HERPES VIRUS | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-27 | — | — | US | disclosed |