Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 13/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 13/20 | 0.42 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904770 | 0.84 | — | — | |
| SCHEMBL9244079 | 0.79 | CYP11B1 (0.51) | CYP11B1CYP11B2TRPV4MAPTAR | |
| SCHEMBL8003064 | 0.78 | TRPV4 (0.40) | CYP11B1CYP11B2TRPV4AR | |
| SCHEMBL14373911 | 0.77 | CYP11B1 (0.49) | CYP11B1CYP11B2TRPV4AR | |
| SCHEMBL6157456 | 0.75 | ALDH1A1 (0.50) | CYP11B1CYP11B2 | |
| SCHEMBL14382331 | 0.75 | ALDH1A1 (0.50) | CYP11B1CYP11B2 | |
| SCHEMBL7907354 | 0.75 | CYP1A2 (0.38) | — | |
| SCHEMBL177036 | 0.74 | CYP11B1 (0.43) | CYP11B1CYP11B2TRPV4SLC22A12 | |
| SCHEMBL13481174 | 0.73 | CYP11B1 (0.51) | CYP11B1CYP11B2TRPV4 | |
| SCHEMBL7323185 | 0.72 | CYP11B1 (0.65) | CYP11B1CYP11B2TRPV4MAPTAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1132377-A1 | Propiolonitrile derivatives and liquid crystal compositions comprising the same | CHISSO CORPORATION (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-6017467-A | HEAT AND CHEMICAL RESISTANCE | CHISSO CORPORATION (JP) | 2000-01-25 | — | — | US | disclosed |
| CN-1174832-A | Propiolonitrile derivatives and liquid crystal compositions comprising the same | CHISSO CORP (JP) | 1998-03-04 | — | — | CN | disclosed |
| EP-0816332-A1 | Propiolonitrile derivatives and liquid crystal compositions comprising the same | Chisso Corporation (JP) | 1998-01-07 | — | — | EP | disclosed |