Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 13/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 13/20 | 0.38 |
| ▸ | DAO | P14920 | 2/20 | 0.37 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904763 | 0.78 | CYP11B1 (0.42) | TRPV4CYP11B1CYP11B2AR | |
| SCHEMBL6928397 | 0.77 | TRPV4 (0.42) | TRPV4CYP11B1CYP11B2DAOCNR1 | |
| SCHEMBL11963202 | 0.75 | TRPV4 (0.50) | TRPV4CYP11B1CYP11B2DAOKCNJ1 | |
| SCHEMBL3631052 | 0.75 | IDO1 (0.41) | — | |
| SCHEMBL9240972 | 0.74 | HSD17B10 (0.49) | TRPV4CYP11B1CYP11B2DAOKCNJ1 | |
| SCHEMBL16892292 | 0.74 | TRPV4 (0.52) | TRPV4CYP11B1CYP11B2DAOCNR1 | |
| SCHEMBL31605567 | 0.74 | TRPV4 (0.52) | TRPV4CYP11B1CYP11B2DAOCNR1 | |
| SCHEMBL13548285 | 0.72 | TRPV4 (0.53) | TRPV4CYP11B1CYP11B2DAOKCNJ1 | |
| SCHEMBL2389038 | 0.71 | TRPV4 (0.57) | TRPV4CYP11B1CYP11B2DAO | |
| SCHEMBL19387960 | 0.70 | TRPV4 (0.47) | TRPV4CYP11B1CYP11B2DAOCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000027627-A1 | ARYLOXIME LINKERS IN THE SOLID-PHASE SYNTHESIS OF 3-AMINOBENZISOXAZOLES | ELI LILLY AND COMPANY (US) | 2000-05-18 | — | — | WO | disclosed |