Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7911570 | 0.91 | MAPK1 (0.41) | MAPK1KDM4EL3MBTL1ABL1S1PR4 | |
| SCHEMBL7906285 | 0.81 | MAPK1 (0.50) | MAPK1KDM4EL3MBTL1PKMRAB9A | |
| SCHEMBL7904907 | 0.80 | MAPK1 (0.46) | MAPK1KDM4EL3MBTL1ABL1S1PR4 | |
| SCHEMBL7906282 | 0.71 | MAPK1 (0.53) | MAPK1KDM4EL3MBTL1NPC1RAB9A | |
| SCHEMBL21957970 | 0.69 | TDP1 (0.43) | KDM4EL3MBTL1PKMRAB9AGABRA5 | |
| SCHEMBL30746942 | 0.67 | MAPK1 (0.46) | MAPK1KDM4EL3MBTL1ABL1PKM | |
| SCHEMBL6902498 | 0.65 | RXRA (0.60) | MAPK1KDM4EL3MBTL1RARARARB | |
| Hydrochloric Acid SCHEMBL6553707 | 0.65 | MAPK1 (0.96) | MAPK1KDM4EL3MBTL1P4HTM | |
| SCHEMBL5830575 | 0.65 | KCNA5 (0.42) | RAB9AKMT2A | |
| SCHEMBL3779621 | 0.65 | KCNA5 (0.42) | RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083888-A1 | MULTIBINDING AGENTS THAT MODULATE PPARgamma AND RXR RECEPTORS | Advanced Medicine, Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999063983-A1 | MULTIBINDING AGENTS THAT MODULATE PPARη AND RXR RECEPTORS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |