Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904908 | 0.81 | MAPK1 (0.42) | MAPK1L3MBTL1KDM4ERAB9APKM | |
| SCHEMBL7906282 | 0.76 | MAPK1 (0.53) | MAPK1L3MBTL1KDM4EMAPTLMNA | |
| SCHEMBL5177723 | 0.72 | LOXL2 (0.59) | MAPK1KDM4EMAPTGAARAB9A | |
| SCHEMBL6902498 | 0.71 | RXRA (0.60) | MAPK1L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL3715093 | 0.71 | MAPK1 (0.54) | MAPK1L3MBTL1KDM4EMAPTGAA | |
| SCHEMBL64700 | 0.69 | MAPK1 (1.00) | MAPK1L3MBTL1KDM4EP4HTM | |
| SCHEMBL69747 | 0.69 | MAPK1 (1.00) | MAPK1L3MBTL1KDM4EMAPTRAB9A | |
| SCHEMBL29508473 | 0.69 | MAPK1 (1.00) | MAPK1L3MBTL1KDM4EMAPTRAB9A | |
| SCHEMBL8688544 | 0.68 | MAPK1 (0.43) | MAPK1L3MBTL1KDM4EMAPTLMNA | |
| SCHEMBL22061332 | 0.68 | MAPK1 (0.72) | MAPK1L3MBTL1KDM4EMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083888-A1 | MULTIBINDING AGENTS THAT MODULATE PPARgamma AND RXR RECEPTORS | Advanced Medicine, Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999063983-A1 | MULTIBINDING AGENTS THAT MODULATE PPARη AND RXR RECEPTORS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |