Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10989774 | 0.84 | GRIK1 (0.32) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL22769569 | 0.72 | MAPT (0.46) | ABCC4MAPT | |
| SCHEMBL654433 | 0.70 | CHRM1 (0.36) | — | |
| SCHEMBL7905059 | 0.70 | GRIK1 (0.34) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL4386669 | 0.70 | GRIK1 (0.50) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL31636 | 0.69 | GRIK1 (0.48) | GRIK1GRIK2CYP2C19CPA1ABCC4 | |
| SCHEMBL5003457 | 0.69 | TDP1 (0.43) | CPA1MAPT | |
| SCHEMBL7437585 | 0.69 | — | — | |
| SCHEMBL2536422 | 0.69 | — | — | |
| SCHEMBL4319153 | 0.69 | TDP1 (0.43) | CPA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516410-B1 | Novel synthesis of 19-nor vitamin D compounds | WISCONSIN ALUMNI RES FOUND (US) | 1998-07-29 | — | — | EP | claimed |