Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.54 |
| ▸ | TNKS | O95271 | 1/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1007616 | 0.82 | MCL1 (0.59) | APPPDK2MCL1BACE1TRPA1 | |
| SCHEMBL12330295 | 0.82 | TNKS (0.57) | ACMSDTNKSTNKS2PTPRCPTPN1 | |
| SCHEMBL27388542 | 0.82 | TNKS (0.53) | ACMSDTNKSTNKS2PTPRCPTPN1 | |
| SCHEMBL27470047 | 0.81 | APP (0.57) | ACMSDAPPMCL1BACE1NPSR1 | |
| SCHEMBL19935596 | 0.79 | TNKS (0.54) | ACMSDTNKSTNKS2PTPRCPTPN1 | |
| SCHEMBL3641688 | 0.79 | TNKS (0.53) | ACMSDTNKSTNKS2PTPRCPTPN1 | |
| SCHEMBL5685946 | 0.79 | ACMSD (0.64) | ACMSDTNKSTNKS2APPPTPRC | |
| SCHEMBL23040370 | 0.78 | TNKS (0.49) | ACMSDTNKSTNKS2PTPRCPTPN1 | |
| SCHEMBL5843391 | 0.78 | ALOX15 (0.57) | ACMSDAPPPTPRCPTPN1PDK2 | |
| SCHEMBL29878768 | 0.78 | ALOX15 (0.57) | ACMSDAPPPTPRCPTPN1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289823-A1 | SUBSTITUTED PYRIDAZINE PHENOL DERIVATIVES | Medshine Discovery Inc. (CN) | 2023-12-13 | — | — | EP | disclosed |
| EP-2615918-A1 | FATTY ACID SYNTHASE INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012037298-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |