Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 3/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15195987 | 0.83 | HDAC4 (0.52) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL30645296 | 0.81 | CYP2A6 (0.48) | HDAC4HDAC2HDAC8HDAC6ALDH1A1 | |
| SCHEMBL8441436 | 0.80 | ALDH1A1 (0.50) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL30605196 | 0.78 | HDAC4 (0.65) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL5378592 | 0.78 | CA2 (0.38) | ALDH1A1HSD17B10HPGD | |
| SCHEMBL60283 | 0.78 | HDAC4 (0.65) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL13045204 | 0.76 | HNF4A (0.48) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL9487300 | 0.75 | HDAC4 (0.62) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL8559182 | 0.75 | HDAC4 (0.62) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL3805586 | 0.75 | HDAC4 (0.62) | HNF4AHDAC4HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204005-B1 | ACCURATE AND SENSITIVE QUALITATIVE OR QUANTITATIVE ANALYSIS BY INCUBATING ANTIBODIES AND COMPETITOR OF DEFINED STRUCTURE IN PRESENCE OF TEST SAMPLE, THEN DETECTING CONGENER | ECOCHEM RESEARCH, INC. | 2001-03-20 | — | — | US | disclosed |