Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.54 |
| ▸ | TSHR | P16473 | 8/20 | 0.54 |
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | AHR | P35869 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29624841 | 0.79 | AHR (0.60) | HSD17B10TSHRHPGDALDH1A1AHR | |
| SCHEMBL4453545 | 0.79 | AHR (0.60) | HSD17B10TSHRHPGDALDH1A1AHR | |
| SCHEMBL9732416 | 0.74 | AHR (0.67) | HSD17B10TSHRHPGDALDH1A1AHR | |
| SCHEMBL6861156 | 0.74 | HSD17B10 (0.78) | HSD17B10TSHRHPGDALDH1A1AHR | |
| SCHEMBL9731778 | 0.74 | HSD17B10 (0.68) | HSD17B10TSHRHPGDALDH1A1AHR | |
| SCHEMBL9796891 | 0.73 | MAPK1 (0.57) | HSD17B10TSHRHPGDALDH1A1AHR | |
| SCHEMBL29386527 | 0.73 | HSD17B10 (0.61) | HSD17B10TSHRHPGDALDH1A1AHR | |
| SCHEMBL6053398 | 0.72 | HSD17B10 (0.72) | HSD17B10TSHRHPGDALDH1A1MAPK1 | |
| 2,2',4,4',5,5'-Hexachlorobiphenyl SCHEMBL29367365 | 0.72 | AHR (1.00) | HSD17B10TSHRHPGDALDH1A1AHR | |
| 2,2',4,4',5,5'-Hexachlorobiphenyl SCHEMBL258301 | 0.72 | AHR (1.00) | HSD17B10TSHRHPGDALDH1A1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204005-B1 | ACCURATE AND SENSITIVE QUALITATIVE OR QUANTITATIVE ANALYSIS BY INCUBATING ANTIBODIES AND COMPETITOR OF DEFINED STRUCTURE IN PRESENCE OF TEST SAMPLE, THEN DETECTING CONGENER | ECOCHEM RESEARCH, INC. | 2001-03-20 | — | — | US | disclosed |
| US-5538852-A | QUALITATIVE OR QUANTITATIVE ANALYSIS WITH COMPETITORS AND ANTIBODIES | ECOCHEM RESEARCH, INC. (US) | 1996-07-23 | — | — | US | disclosed |