SCHEMBL29624841

SCHEMBL29624841

Clc1cc(Cl)c(Cl)c(-c2cc(Cl)c(Cl)cc2Cl)c1

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AHR P35869 9/20 0.60
MAPK1 P28482 1/20 0.60
ALDH1A1 P00352 3/20 0.52
TSHR P16473 3/20 0.42
HSD17B10 Q99714 3/20 0.42
HPGD P15428 2/20 0.42
CYP3A4 P08684 2/20 0.41
SCN2A Q99250 4/20 0.39
CASP1 P29466 1/20 0.36
RECQL P46063 1/20 0.36
TP53 P04637 1/20 0.36
SCN9A Q15858 3/20 0.35
SCN3A Q9NY46 3/20 0.35
SCN10A Q9Y5Y9 3/20 0.35
SCN1A P35498 1/20 0.35
KCNH2 Q12809 1/20 0.35
SCN5A Q14524 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4453545 1.00 AHR (0.60) AHRMAPK1ALDH1A1TSHRHSD17B10
SCHEMBL2930780 0.87 ALDH1A1 (0.69) AHRALDH1A1TSHRHSD17B10HPGD
SCHEMBL30035850 0.82 ALDH1A1 (0.55) AHRALDH1A1TSHRHSD17B10HPGD
SCHEMBL4453636 0.82 ALDH1A1 (0.55) AHRALDH1A1TSHRHSD17B10HPGD
SCHEMBL7905262 0.79 HSD17B10 (0.54) AHRMAPK1ALDH1A1TSHRHSD17B10
SCHEMBL29366112 0.79 AHR (0.67) AHRMAPK1ALDH1A1TSHRHSD17B10
SCHEMBL4459067 0.79 ALDH1A1 (0.58) AHRMAPK1ALDH1A1TSHRHSD17B10
SCHEMBL4452334 0.79 AHR (0.67) AHRMAPK1ALDH1A1TSHRHSD17B10
SCHEMBL4454535 0.78 TP53 (0.52) AHRALDH1A1TSHRHSD17B10HPGD
SCHEMBL4450035 0.78 AHR (0.61) AHRALDH1A1TSHRHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220351865-A1 METHODS OF BIOLOGICAL AGE EVALUATION AND SYSTEMS USING SUCH METHODS GERO PTE. LTD. (SG) 2022-11-03 US claimed
CN-114087563-B Lamp with lateral drainage heat dissipation channel 江门市思坎普科技有限公司 2024-03-26 CN disclosed
US-20230330725-A1 VOLATILIZATION AND OXIDATION OF ORGANIC WASTE NATIONAL BANK OF CANADA (CA) 2023-10-19 US disclosed
US-20230047816-A1 PFKFB3 INHIBITORS AND THEIR USES GERO PTE. LTD. (SG) 2023-02-16 US disclosed
US-20220351865-A1 METHODS OF BIOLOGICAL AGE EVALUATION AND SYSTEMS USING SUCH METHODS GERO PTE. LTD. (SG) 2022-11-03 US disclosed
CN-114634886-A Multifunctional microbial agent capable of degrading various halogenated organic pollutants simultaneously 河南科技大学 2022-06-17 CN disclosed
CN-114394680-A Application of microbial agent in degradation of various halogenated organic pollutants 河南科技大学 2022-04-26 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230047816-A1 PFKFB3 INHIBITORS AND THEIR USES PFKFB3, PFKFB4, PFKFB1 AHR 3353/4885MAPK1 1468/4885ALDH1A1 1943/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.