Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | FBP1 | P09467 | 1/20 | 0.56 |
| ▸ | VCP | P55072 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905287 | 1.00 | NFE2L2 (0.67) | NFE2L2KMT2AGAAHTTALDH1A1 | |
| SCHEMBL7907892 | 0.91 | NFE2L2 (0.62) | NFE2L2KMT2AGAAHTTALDH1A1 | |
| SCHEMBL7907894 | 0.91 | NFE2L2 (0.62) | NFE2L2KMT2AGAAHTTALDH1A1 | |
| SCHEMBL28813938 | 0.84 | CYP1B1 (0.53) | NFE2L2KMT2AALDH1A1FBP1CYP19A1 | |
| SCHEMBL27980282 | 0.84 | CYP1B1 (0.53) | NFE2L2KMT2AALDH1A1FBP1CYP19A1 | |
| SCHEMBL1405312 | 0.81 | NFE2L2 (1.00) | NFE2L2KMT2AHTTALDH1A1FBP1 | |
| SCHEMBL1405314 | 0.81 | NFE2L2 (1.00) | NFE2L2KMT2AHTTALDH1A1FBP1 | |
| SCHEMBL9062715 | 0.80 | NFE2L2 (0.63) | NFE2L2KMT2AGAAHTTALDH1A1 | |
| SCHEMBL28849939 | 0.80 | NFE2L2 (0.63) | NFE2L2KMT2AGAAHTTALDH1A1 | |
| SCHEMBL9062717 | 0.80 | NFE2L2 (0.63) | NFE2L2KMT2AGAAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191718-A | A kind of method for synthesizing (E)-(2- (benzenesulfonyl) vinyl) benzene and its derivative | 湖南农业大学 | 2018-06-22 | — | — | CN | disclosed |
| US-6201131-B1 | REACTING A 2-(ARYLSUFONYL) ETHANOL DERIVATIVE WITH AN ACID ANHYDRIDE IN PRESENCE OF A BASE, FURTHER REACTING THIS WITH AN AROMATIC HALIDE IN THE PRESENCE OF A PALLADIUM CATALYST; USEFUL AS INTERMEDIATES TO DRUGS, AGROCHEMICALS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-03-13 | — | — | US | disclosed |