Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | FBP1 | P09467 | 1/20 | 0.49 |
| ▸ | VCP | P55072 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907892 | 1.00 | NFE2L2 (0.62) | NFE2L2KMT2AGAAHTTCA2 | |
| SCHEMBL7905287 | 0.91 | NFE2L2 (0.67) | NFE2L2KMT2AGAAHTTCA2 | |
| SCHEMBL7905289 | 0.91 | NFE2L2 (0.67) | NFE2L2KMT2AGAAHTTCA2 | |
| SCHEMBL28813938 | 0.84 | CYP1B1 (0.53) | NFE2L2KMT2ACA2CA5ACA1 | |
| SCHEMBL27980282 | 0.84 | CYP1B1 (0.53) | NFE2L2KMT2ACA2CA5ACA1 | |
| SCHEMBL3477247 | 0.79 | KMT2A (0.89) | NFE2L2KMT2AGAAHTTCA2 | |
| SCHEMBL1405314 | 0.77 | NFE2L2 (1.00) | NFE2L2KMT2AHTTALDH1A1CYP19A1 | |
| SCHEMBL1405312 | 0.77 | NFE2L2 (1.00) | NFE2L2KMT2AHTTALDH1A1CYP19A1 | |
| SCHEMBL9580710 | 0.77 | KMT2A (1.00) | KMT2AGAAHTTCA2CA5A | |
| SCHEMBL5572469 | 0.77 | TLR9 (0.64) | NFE2L2KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201131-B1 | REACTING A 2-(ARYLSUFONYL) ETHANOL DERIVATIVE WITH AN ACID ANHYDRIDE IN PRESENCE OF A BASE, FURTHER REACTING THIS WITH AN AROMATIC HALIDE IN THE PRESENCE OF A PALLADIUM CATALYST; USEFUL AS INTERMEDIATES TO DRUGS, AGROCHEMICALS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-03-13 | — | — | US | disclosed |