Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | FBP1 | P09467 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28813938 | 1.00 | CYP1B1 (0.53) | CYP1B1NFE2L2CYP19A1CTSKBCHE | |
| SCHEMBL7907894 | 0.84 | NFE2L2 (0.62) | NFE2L2CYP19A1MAOBCA2ALDH1A1 | |
| SCHEMBL7905289 | 0.84 | NFE2L2 (0.67) | NFE2L2CYP19A1MAOBCA2ALDH1A1 | |
| SCHEMBL7905287 | 0.84 | NFE2L2 (0.67) | NFE2L2CYP19A1MAOBCA2ALDH1A1 | |
| SCHEMBL7907892 | 0.84 | NFE2L2 (0.62) | NFE2L2CYP19A1MAOBCA2ALDH1A1 | |
| SCHEMBL1925183 | 0.84 | ACHE (0.56) | NFE2L2BCHEMAOBAPPALDH1A1 | |
| SCHEMBL4478513 | 0.84 | ACHE (0.56) | NFE2L2BCHEMAOBAPPALDH1A1 | |
| SCHEMBL5572469 | 0.82 | TLR9 (0.64) | NFE2L2ALDH1A1LMNAKMT2AEGFR | |
| SCHEMBL29149692 | 0.82 | TLR9 (0.64) | NFE2L2ALDH1A1LMNAKMT2AEGFR | |
| SCHEMBL5572462 | 0.82 | TLR9 (0.64) | NFE2L2ALDH1A1LMNAKMT2AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104000805-B | Styryl-sulfamide compound is preparing the application in anti-HIV-1 virus drugs | Guangzhou Zhongheng Electronic Technology Co.,Ltd. (CN) | 2016-03-02 | — | — | CN | disclosed |
| CN-104000805-A | Application of styryl-sulfonamide compounds to preparation of HIV-1 (Human Immunodeficiency Virus-1)-resistant drugs | UNIV SUN YAT SEN | 2014-08-27 | — | — | CN | disclosed |
| CN-104000805-A | Application of styryl-sulfonamide compounds to preparation of HIV-1 (Human Immunodeficiency Virus-1)-resistant drugs | UNIV SUN YAT SEN | 2014-08-27 | — | — | CN | disclosed |